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Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients.
Bergamaschi MM, Queiroz RH, Chagas MH, de Oliveira DC, De Martinis BS, Kapczinski F, Quevedo J, Roesler R, Schröder N, Nardi AE, Martín-Santos R, Hallak JE, Zuardi AW, Crippa JA. Bergamaschi MM, et al. Among authors: Roesler R. Neuropsychopharmacology. 2011 May;36(6):1219-26. doi: 10.1038/npp.2011.6. Epub 2011 Feb 9. Neuropsychopharmacology. 2011. PMID: 21307846 Free PMC article. Clinical Trial.
Non-associative learning and anxiety in rats treated with a single systemic administration of the gastrin-releasing peptide receptor antagonist RC-3095.
Martins MR, Reinke A, Valvassori SS, Machado RA, Quevedo J, Schwartsmann G, Roesler R. Martins MR, et al. Among authors: Roesler R. Peptides. 2005 Dec;26(12):2525-9. doi: 10.1016/j.peptides.2005.06.006. Epub 2005 Jul 14. Peptides. 2005. PMID: 16023260
Bombesin receptor regulation of emotional memory.
Roesler R, Kent P, Schroder N, Schwartsmann G, Merali Z. Roesler R, et al. Rev Neurosci. 2012;23(5-6):571-86. doi: 10.1515/revneuro-2012-0046. Rev Neurosci. 2012. PMID: 23096238 Review.
Viability of D283 medulloblastoma cells treated with a histone deacetylase inhibitor combined with bombesin receptor antagonists.
Jaeger M, Ghisleni EC, Fratini L, Brunetto AL, Gregianin LJ, Brunetto AT, Schwartsmann G, de Farias CB, Roesler R. Jaeger M, et al. Among authors: Roesler R. Childs Nerv Syst. 2016 Jan;32(1):61-4. doi: 10.1007/s00381-015-2963-4. Epub 2015 Nov 20. Childs Nerv Syst. 2016. PMID: 26590027
Gastrin-releasing peptide receptor antagonism induces protection from lethal sepsis: involvement of toll-like receptor 4 signaling.
Petronilho F, Vuolo F, Galant LS, Constantino L, Tomasi CD, Giombelli VR, de Souza CT, da Silva S, Barbeiro DF, Soriano FG, Streck EL, Ritter C, Zanotto-Filho A, Pasquali MA, Gelain DP, Rybarczyk-Filho JL, Moreira JC, Block NL, Roesler R, Schwartsmann G, Schally AV, Dal-Pizzol F. Petronilho F, et al. Among authors: Roesler R. Mol Med. 2012 Oct 24;18(1):1209-19. doi: 10.2119/molmed.2012.00083. Mol Med. 2012. PMID: 22735756 Free PMC article. Clinical Trial.
Rescue of social behavior impairment by clozapine and alterations in the expression of neuronal receptors in a rat model of neurodevelopmental impairment induced by GRPR blockade.
Presti-Torres J, Garcia VA, Dornelles A, Halmenschlager LH, Alcalde LA, Vedana G, Rico EP, Bogo MR, Schwartsmann G, Roesler R, Schröder N. Presti-Torres J, et al. Among authors: Roesler R. J Neural Transm (Vienna). 2012 Mar;119(3):319-27. doi: 10.1007/s00702-011-0695-5. Epub 2011 Aug 17. J Neural Transm (Vienna). 2012. PMID: 21847557
Gastrin-releasing peptide receptor antagonist or N-acetylcysteine combined with omeprazol protect against mitochondrial complex II inhibition in a rat model of gastritis.
Rezin GT, Petronilho FC, Araújo JH, Gonçalves CL, Daufenbach JF, Cardoso MR, Roesler R, Schwartsmann G, Dal-Pizzol F, Streck EL. Rezin GT, et al. Among authors: Roesler R. Basic Clin Pharmacol Toxicol. 2011 Mar;108(3):214-9. doi: 10.1111/j.1742-7843.2010.00645.x. Epub 2010 Dec 8. Basic Clin Pharmacol Toxicol. 2011. PMID: 21138529
Effects of N-acetylcysteine/deferoxamine, taurine and RC-3095 on respiratory chain complexes and creatine kinase activities in rat brain after sepsis.
Cassol OJ Jr, Rezin GT, Petronilho FC, Scaini G, Gonçalves CL, Ferreira GK, Roesler R, Schwartsmann G, Dal-Pizzol F, Streck EL. Cassol OJ Jr, et al. Among authors: Roesler R. Neurochem Res. 2010 Apr;35(4):515-21. doi: 10.1007/s11064-009-0089-3. Neurochem Res. 2010. PMID: 20238483
Gastrin-Releasing Peptide Receptor Knockdown Induces Senescence in Glioblastoma Cells.
Menegotto PR, da Costa Lopez PL, Souza BK, de Farias CB, Filippi-Chiela EC, Vieira IA, Schwartsmann G, Lenz G, Roesler R. Menegotto PR, et al. Among authors: Roesler R. Mol Neurobiol. 2017 Mar;54(2):888-894. doi: 10.1007/s12035-016-9696-6. Epub 2016 Jan 16. Mol Neurobiol. 2017. PMID: 26780458
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