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Identification of a novel phosphonocarboxylate inhibitor of Rab geranylgeranyl transferase that specifically prevents Rab prenylation in osteoclasts and macrophages.
Coxon FP, Helfrich MH, Larijani B, Muzylak M, Dunford JE, Marshall D, McKinnon AD, Nesbitt SA, Horton MA, Seabra MC, Ebetino FH, Rogers MJ. Coxon FP, et al. Among authors: rogers mj. J Biol Chem. 2001 Dec 21;276(51):48213-22. doi: 10.1074/jbc.M106473200. Epub 2001 Oct 1. J Biol Chem. 2001. PMID: 11581260
Cellular and molecular mechanisms of action of bisphosphonates.
Rogers MJ, Gordon S, Benford HL, Coxon FP, Luckman SP, Monkkonen J, Frith JC. Rogers MJ, et al. Cancer. 2000 Jun 15;88(12 Suppl):2961-78. doi: 10.1002/1097-0142(20000615)88:12+<2961::aid-cncr12>;2-c. Cancer. 2000. PMID: 10898340 Review.
Anti-tumour activity of bisphosphonates in human myeloma cells.
Shipman CM, Rogers MJ, Apperley JF, Graham R, Russell G, Croucher PI. Shipman CM, et al. Among authors: rogers mj. Leuk Lymphoma. 1998 Dec;32(1-2):129-38. doi: 10.3109/10428199809059253. Leuk Lymphoma. 1998. PMID: 10037008 Review.
Molecular mechanisms of action of bisphosphonates.
Rogers MJ, Frith JC, Luckman SP, Coxon FP, Benford HL, Mönkkönen J, Auriola S, Chilton KM, Russell RG. Rogers MJ, et al. Bone. 1999 May;24(5 Suppl):73S-79S. doi: 10.1016/s8756-3282(99)00070-8. Bone. 1999. PMID: 10321934 Review. No abstract available.
The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis.
Frith JC, Mönkkönen J, Auriola S, Mönkkönen H, Rogers MJ. Frith JC, et al. Among authors: rogers mj. Arthritis Rheum. 2001 Sep;44(9):2201-10. doi: 10.1002/1529-0131(200109)44:9<2201::aid-art374>;2-e. Arthritis Rheum. 2001. PMID: 11592386
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