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The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions.
Daugaard M, Rohde M, Jäättelä M. Daugaard M, et al. Among authors: rohde m. FEBS Lett. 2007 Jul 31;581(19):3702-10. doi: 10.1016/j.febslet.2007.05.039. Epub 2007 May 25. FEBS Lett. 2007. PMID: 17544402 Review.
Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase.
Petersen NH, Olsen OD, Groth-Pedersen L, Ellegaard AM, Bilgin M, Redmer S, Ostenfeld MS, Ulanet D, Dovmark TH, Lønborg A, Vindeløv SD, Hanahan D, Arenz C, Ejsing CS, Kirkegaard T, Rohde M, Nylandsted J, Jäättelä M. Petersen NH, et al. Among authors: rohde m. Cancer Cell. 2013 Sep 9;24(3):379-93. doi: 10.1016/j.ccr.2013.08.003. Cancer Cell. 2013. PMID: 24029234
LEDGF (p75) promotes DNA-end resection and homologous recombination.
Daugaard M, Baude A, Fugger K, Povlsen LK, Beck H, Sørensen CS, Petersen NH, Sorensen PH, Lukas C, Bartek J, Lukas J, Rohde M, Jäättelä M. Daugaard M, et al. Among authors: rohde m. Nat Struct Mol Biol. 2012 Aug;19(8):803-10. doi: 10.1038/nsmb.2314. Epub 2012 Jul 8. Nat Struct Mol Biol. 2012. PMID: 22773103
Lens epithelium-derived growth factor is an Hsp70-2 regulated guardian of lysosomal stability in human cancer.
Daugaard M, Kirkegaard-Sørensen T, Ostenfeld MS, Aaboe M, Høyer-Hansen M, Orntoft TF, Rohde M, Jäättelä M. Daugaard M, et al. Among authors: rohde m. Cancer Res. 2007 Mar 15;67(6):2559-67. doi: 10.1158/0008-5472.CAN-06-4121. Cancer Res. 2007. PMID: 17363574
Hsp70-2 is required for tumor cell growth and survival.
Daugaard M, Jäättelä M, Rohde M. Daugaard M, et al. Among authors: rohde m. Cell Cycle. 2005 Jul;4(7):877-80. doi: 10.4161/cc.4.7.1838. Epub 2005 Jul 11. Cell Cycle. 2005. PMID: 15970673
Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms.
Rohde M, Daugaard M, Jensen MH, Helin K, Nylandsted J, Jäättelä M. Rohde M, et al. Genes Dev. 2005 Mar 1;19(5):570-82. doi: 10.1101/gad.305405. Genes Dev. 2005. PMID: 15741319 Free PMC article.
Eradication of glioblastoma, and breast and colon carcinoma xenografts by Hsp70 depletion.
Nylandsted J, Wick W, Hirt UA, Brand K, Rohde M, Leist M, Weller M, Jäättelä M. Nylandsted J, et al. Among authors: rohde m. Cancer Res. 2002 Dec 15;62(24):7139-42. Cancer Res. 2002. PMID: 12499245
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization.
Nylandsted J, Gyrd-Hansen M, Danielewicz A, Fehrenbacher N, Lademann U, Høyer-Hansen M, Weber E, Multhoff G, Rohde M, Jäättelä M. Nylandsted J, et al. Among authors: rohde m. J Exp Med. 2004 Aug 16;200(4):425-35. doi: 10.1084/jem.20040531. J Exp Med. 2004. PMID: 15314073 Free PMC article.
Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination.
Baude A, Aaes TL, Zhai B, Al-Nakouzi N, Oo HZ, Daugaard M, Rohde M, Jäättelä M. Baude A, et al. Among authors: rohde m. Nucleic Acids Res. 2016 Mar 18;44(5):2214-26. doi: 10.1093/nar/gkv1526. Epub 2015 Dec 31. Nucleic Acids Res. 2016. PMID: 26721387 Free PMC article.
Expression of a p16INK4a-specific ribozyme downmodulates p16INK4a abundance and accelerates cell proliferation.
Nylandsted J, Rohde M, Bartek J, Strauss M. Nylandsted J, et al. Among authors: rohde m. FEBS Lett. 1998 Sep 25;436(1):41-5. doi: 10.1016/s0014-5793(98)01089-8. FEBS Lett. 1998. PMID: 9771890
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