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Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity.
Passini E, Britton OJ, Lu HR, Rohrbacher J, Hermans AN, Gallacher DJ, Greig RJH, Bueno-Orovio A, Rodriguez B. Passini E, et al. Among authors: rohrbacher j. Front Physiol. 2017 Sep 12;8:668. doi: 10.3389/fphys.2017.00668. eCollection 2017. Front Physiol. 2017. PMID: 28955244 Free PMC article.
Predicting drug-induced slowing of conduction and pro-arrhythmia: identifying the 'bad' sodium current blockers.
Lu HR, Rohrbacher J, Vlaminckx E, Van Ammel K, Yan GX, Gallacher DJ. Lu HR, et al. Among authors: rohrbacher j. Br J Pharmacol. 2010 May;160(1):60-76. doi: 10.1111/j.1476-5381.2010.00646.x. Epub 2010 Mar 22. Br J Pharmacol. 2010. PMID: 20331615 Free PMC article.
In-vitro experimental models for the risk assessment of antibiotic-induced QT prolongation.
Lu HR, Vlaminckx E, Van de Water A, Rohrbacher J, Hermans A, Gallacher DJ. Lu HR, et al. Eur J Pharmacol. 2007 Dec 22;577(1-3):222-32. doi: 10.1016/j.ejphar.2007.07.070. Eur J Pharmacol. 2007. PMID: 18074444
In-vitro experimental models for the risk assessment of antibiotic-induced QT prolongation.
Lu HR, Vlaminckx E, Van de Water A, Rohrbacher J, Hermans A, Gallacher DJ. Lu HR, et al. Eur J Pharmacol. 2006 Dec 28;553(1-3):229-39. doi: 10.1016/j.ejphar.2006.09.035. Epub 2006 Sep 23. Eur J Pharmacol. 2006. PMID: 17054943 Corrected and republished.
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