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DDX21: The link between m6A and R-loops.
Lavergne G, Roignant JY. Lavergne G, et al. Among authors: roignant jy. Mol Cell. 2024 May 2;84(9):1631-1632. doi: 10.1016/j.molcel.2024.04.005. Mol Cell. 2024. PMID: 38701738
Mechanistic insights into m6A RNA enzymes.
Lence T, Paolantoni C, Worpenberg L, Roignant JY. Lence T, et al. Among authors: roignant jy. Biochim Biophys Acta Gene Regul Mech. 2019 Mar;1862(3):222-229. doi: 10.1016/j.bbagrm.2018.10.014. Epub 2018 Nov 3. Biochim Biophys Acta Gene Regul Mech. 2019. PMID: 30395944 Review.
Hakai is required for stabilization of core components of the m6A mRNA methylation machinery.
Bawankar P, Lence T, Paolantoni C, Haussmann IU, Kazlauskiene M, Jacob D, Heidelberger JB, Richter FM, Nallasivan MP, Morin V, Kreim N, Beli P, Helm M, Jinek M, Soller M, Roignant JY. Bawankar P, et al. Among authors: roignant jy. Nat Commun. 2021 Jun 18;12(1):3778. doi: 10.1038/s41467-021-23892-5. Nat Commun. 2021. PMID: 34145251 Free PMC article.
Poly(m6A) tails stabilize transcripts.
Lavergne G, Roignant JY. Lavergne G, et al. Among authors: roignant jy. Mol Cell. 2022 Jun 2;82(11):1979-1980. doi: 10.1016/j.molcel.2022.05.017. Mol Cell. 2022. PMID: 35659324 Free article.
m6A modulates neuronal functions and sex determination in Drosophila.
Lence T, Akhtar J, Bayer M, Schmid K, Spindler L, Ho CH, Kreim N, Andrade-Navarro MA, Poeck B, Helm M, Roignant JY. Lence T, et al. Among authors: roignant jy. Nature. 2016 Dec 8;540(7632):242-247. doi: 10.1038/nature20568. Epub 2016 Nov 30. Nature. 2016. PMID: 27919077
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d.
Knuckles P, Lence T, Haussmann IU, Jacob D, Kreim N, Carl SH, Masiello I, Hares T, Villaseñor R, Hess D, Andrade-Navarro MA, Biggiogera M, Helm M, Soller M, Bühler M, Roignant JY. Knuckles P, et al. Among authors: roignant jy. Genes Dev. 2018 Mar 1;32(5-6):415-429. doi: 10.1101/gad.309146.117. Epub 2018 Mar 13. Genes Dev. 2018. PMID: 29535189 Free PMC article.
48 results