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Role of Mitochondrial Complex IV in Age-Dependent Obesity.
Soro-Arnaiz I, Li QOY, Torres-Capelli M, Meléndez-Rodríguez F, Veiga S, Veys K, Sebastian D, Elorza A, Tello D, Hernansanz-Agustín P, Cogliati S, Moreno-Navarrete JM, Balsa E, Fuertes E, Romanos E, Martínez-Ruiz A, Enriquez JA, Fernandez-Real JM, Zorzano A, De Bock K, Aragonés J. Soro-Arnaiz I, et al. Cell Rep. 2016 Sep 13;16(11):2991-3002. doi: 10.1016/j.celrep.2016.08.041. Cell Rep. 2016. PMID: 27626667 Free article.
Aging is associated with progressive white adipose tissue (WAT) enlargement initiated early in life, but the molecular mechanisms involved remain unknown. Here we show that mitochondrial complex IV (CIV) activity and assembly are already repressed in white ad …
Aging is associated with progressive white adipose tissue (WAT) enlargement initiated early in life, but the molecular mechanisms involved r …
Targeting Multiple Mitochondrial Processes by a Metabolic Modulator Prevents Sarcopenia and Cognitive Decline in SAMP8 Mice.
Brunetti D, Bottani E, Segala A, Marchet S, Rossi F, Orlando F, Malavolta M, Carruba MO, Lamperti C, Provinciali M, Nisoli E, Valerio A. Brunetti D, et al. Front Pharmacol. 2020 Jul 31;11:1171. doi: 10.3389/fphar.2020.01171. eCollection 2020. Front Pharmacol. 2020. PMID: 32848778 Free PMC article.
The age-dependent declines of skeletal muscle and cognitive functions often coexist in elderly subjects. ...The PD-0E7 mixture increased the protein levels and the enzymatic activities of mitochondrial complex I, II, and IV and the expression of …
The age-dependent declines of skeletal muscle and cognitive functions often coexist in elderly subjects. ...The PD-0E7 mixture …