Rollins S - Search Results

1

Pharmacology and biological efficacy of a recombinant, humanized, single-chain antibody C5 complement inhibitor in patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass.

Fitch JC, Rollins S, Matis L, Alford B, Aranki S, Collard CD, Dewar M, Elefteriades J, Hines R, Kopf G, Kraker P, Li L, O'Hara R, Rinder C, Rinder H, Shaw R, Smith B, Stahl G, Shernan SK. Fitch JC, et al. Among authors: rollins s. Circulation. 1999 Dec 21-28;100(25):2499-506. doi: 10.1161/01.cir.100.25.2499. Circulation. 1999. PMID: 10604887 Clinical Trial.

2

Blockade of C5a and C5b-9 generation inhibits leukocyte and platelet activation during extracorporeal circulation.

Rinder CS, Rinder HM, Smith BR, Fitch JC, Smith MJ, Tracey JB, Matis LA, Squinto SP, Rollins SA. Rinder CS, et al. Among authors: rollins sa. J Clin Invest. 1995 Sep;96(3):1564-72. doi: 10.1172/JCI118195. J Clin Invest. 1995. PMID: 7657827 Free PMC article.

3

Myocardial infarction and apoptosis after myocardial ischemia and reperfusion: role of the terminal complement components and inhibition by anti-C5 therapy.

Vakeva AP, Agah A, Rollins SA, Matis LA, Li L, Stahl GL. Vakeva AP, et al. Among authors: rollins sa. Circulation. 1998 Jun 9;97(22):2259-67. doi: 10.1161/01.cir.97.22.2259. Circulation. 1998. PMID: 9631876

4

Antithrombin reduces monocyte and neutrophil CD11b up regulation in addition to blocking platelet activation during extracorporeal circulation.

Rinder CS, Rinder HM, Smith MJ, Fitch JC, Tracey JB, Chandler WL, Rollins SA, Smith BR. Rinder CS, et al. Among authors: rollins sa. Transfusion. 2006 Jul;46(7):1130-7. doi: 10.1111/j.1537-2995.2006.00861.x. Transfusion. 2006. PMID: 16836559

5

Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease.

Wang Y, Rollins SA, Madri JA, Matis LA. Wang Y, et al. Among authors: rollins sa. Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8955-9. doi: 10.1073/pnas.92.19.8955. Proc Natl Acad Sci U S A. 1995. PMID: 7568051 Free PMC article.

6

Complement-specific antibodies: designing novel anti-inflammatories.

Matis LA, Rollins SA. Matis LA, et al. Among authors: rollins sa. Nat Med. 1995 Aug;1(8):839-42. doi: 10.1038/nm0895-839. Nat Med. 1995. PMID: 7585191 Free PMC article. Review. No abstract available.

7

Amelioration of lupus-like autoimmune disease in NZB/WF1 mice after treatment with a blocking monoclonal antibody specific for complement component C5.

Wang Y, Hu Q, Madri JA, Rollins SA, Chodera A, Matis LA. Wang Y, et al. Among authors: rollins sa. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8563-8. doi: 10.1073/pnas.93.16.8563. Proc Natl Acad Sci U S A. 1996. PMID: 8710910 Free PMC article.

8

Inhibition of complement activity by humanized anti-C5 antibody and single-chain Fv.

Thomas TC, Rollins SA, Rother RP, Giannoni MA, Hartman SL, Elliott EA, Nye SH, Matis LA, Squinto SP, Evans MJ. Thomas TC, et al. Among authors: rollins sa. Mol Immunol. 1996 Dec;33(17-18):1389-401. doi: 10.1016/s0161-5890(96)00078-8. Mol Immunol. 1996. PMID: 9171898

9

Selective blockade of membrane attack complex formation during simulated extracorporeal circulation inhibits platelet but not leukocyte activation.

Rinder CS, Rinder HM, Smith MJ, Tracey JB, Fitch J, Li L, Rollins SA, Smith BR. Rinder CS, et al. Among authors: rollins sa. J Thorac Cardiovasc Surg. 1999 Sep;118(3):460-6. doi: 10.1016/S0022-5223(99)70183-2. J Thorac Cardiovasc Surg. 1999. PMID: 10469960 Free article.

10

Impact of pexelizumab, an anti-C5 complement antibody, on total mortality and adverse cardiovascular outcomes in cardiac surgical patients undergoing cardiopulmonary bypass.

Shernan SK, Fitch JC, Nussmeier NA, Chen JC, Rollins SA, Mojcik CF, Malloy KJ, Todaro TG, Filloon T, Boyce SW, Gangahar DM, Goldberg M, Saidman LJ, Mangano DT; Pexelizumab Study Investigators. Shernan SK, et al. Ann Thorac Surg. 2004 Mar;77(3):942-9; discussion 949-50. doi: 10.1016/j.athoracsur.2003.08.054. Ann Thorac Surg. 2004. PMID: 14992903 Clinical Trial.

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