Roman DL - Search Results

1

A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen.

Roof RA, Roman DL, Clements ST, Sobczyk-Kojiro K, Blazer LL, Ota S, Mosberg HI, Neubig RR. Roof RA, et al. Among authors: roman dl. BMC Pharmacol. 2009 May 22;9:9. doi: 10.1186/1471-2210-9-9. BMC Pharmacol. 2009. PMID: 19463173 Free PMC article.

2

Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins.

Roof RA, Jin Y, Roman DL, Sunahara RK, Ishii M, Mosberg HI, Neubig RR. Roof RA, et al. Among authors: roman dl. Chem Biol Drug Des. 2006 Apr;67(4):266-74. doi: 10.1111/j.1747-0285.2006.00373.x. Chem Biol Drug Des. 2006. PMID: 16629824 Free article.

3

Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay.

Roman DL, Talbot JN, Roof RA, Sunahara RK, Traynor JR, Neubig RR. Roman DL, et al. Mol Pharmacol. 2007 Jan;71(1):169-75. doi: 10.1124/mol.106.028670. Epub 2006 Sep 29. Mol Pharmacol. 2007. PMID: 17012620

4

Novel peptide ligands of RGS4 from a focused one-bead, one-compound library.

Roof RA, Sobczyk-Kojiro K, Turbiak AJ, Roman DL, Pogozheva ID, Blazer LL, Neubig RR, Mosberg HI. Roof RA, et al. Among authors: roman dl. Chem Biol Drug Des. 2008 Aug;72(2):111-9. doi: 10.1111/j.1747-0285.2008.00687.x. Epub 2008 Jul 15. Chem Biol Drug Des. 2008. PMID: 18637987 Free PMC article.

5

Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins.

Blazer LL, Roman DL, Chung A, Larsen MJ, Greedy BM, Husbands SM, Neubig RR. Blazer LL, et al. Among authors: roman dl. Mol Pharmacol. 2010 Sep;78(3):524-33. doi: 10.1124/mol.110.065128. Epub 2010 Jun 22. Mol Pharmacol. 2010. PMID: 20571077 Free PMC article.

6

In vitro protein kinase activity measurement by flow cytometry.

Bernsteel DJ, Roman DL, Neubig RR. Bernsteel DJ, et al. Among authors: roman dl. Anal Biochem. 2008 Dec 15;383(2):180-5. doi: 10.1016/j.ab.2008.08.026. Epub 2008 Sep 3. Anal Biochem. 2008. PMID: 18796290

7

Polyplexed flow cytometry protein interaction assay: a novel high-throughput screening paradigm for RGS protein inhibitors.

Roman DL, Ota S, Neubig RR. Roman DL, et al. J Biomol Screen. 2009 Jul;14(6):610-9. doi: 10.1177/1087057109336590. Epub 2009 Jun 16. J Biomol Screen. 2009. PMID: 19531661 Free PMC article.

8

Differential modulation of mu-opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Galpha subtype dependent.

Talbot JN, Roman DL, Clark MJ, Roof RA, Tesmer JJ, Neubig RR, Traynor JR. Talbot JN, et al. Among authors: roman dl. J Neurochem. 2010 Feb;112(4):1026-34. doi: 10.1111/j.1471-4159.2009.06519.x. Epub 2009 Nov 30. J Neurochem. 2010. PMID: 20002516 Free PMC article.

9

Use of flow cytometric methods to quantify protein-protein interactions.

Blazer LL, Roman DL, Muxlow MR, Neubig RR. Blazer LL, et al. Among authors: roman dl. Curr Protoc Cytom. 2010 Jan;Chapter 13:Unit 13.11.1-15. doi: 10.1002/0471142956.cy1311s51. Curr Protoc Cytom. 2010. PMID: 20069525 Free PMC article.

10

Allosteric inhibition of the regulator of G protein signaling-Galpha protein-protein interaction by CCG-4986.

Roman DL, Blazer LL, Monroy CA, Neubig RR. Roman DL, et al. Mol Pharmacol. 2010 Sep;78(3):360-5. doi: 10.1124/mol.109.063388. Epub 2010 Jun 7. Mol Pharmacol. 2010. PMID: 20530129 Free PMC article.

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