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Perseveration related to frontal lesion in mice using the olfactory H-maze.
Del'Guidice T, Nivet E, Escoffier G, Baril N, Caverni JP, Roman FS. Del'Guidice T, et al. Among authors: roman fs. Behav Brain Res. 2009 Dec 14;205(1):226-33. doi: 10.1016/j.bbr.2009.08.007. Epub 2009 Aug 14. Behav Brain Res. 2009. PMID: 19683547
In the current study, mouse experiments were conducted using a new, totally automated device, the olfactory H-maze. Here, we show that unilateral lesion of the dorsomedial prefrontal cortex in mice induced similar deficits to those observed after frontal lesions in …
In the current study, mouse experiments were conducted using a new, totally automated device, the olfactory H-maze. Here, we s …
MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitro.
Baranger K, Bonnet AE, Girard SD, Paumier JM, García-González L, Elmanaa W, Bernard A, Charrat E, Stephan D, Bauer C, Moschke K, Lichtenthaler SF, Roman FS, Checler F, Khrestchatisky M, Rivera S. Baranger K, et al. Among authors: roman fs. Front Mol Neurosci. 2017 Jan 10;9:163. doi: 10.3389/fnmol.2016.00163. eCollection 2016. Front Mol Neurosci. 2017. PMID: 28119565 Free PMC article.
We have now investigated whether the integrity of another important area affected in Alzheimer's disease (AD), the frontal cortex, was also preserved upon MT5-MMP deficiency in 4-month old mice at prodromal stages of the pathology. We used the olfactory H-maze (OHM) …
We have now investigated whether the integrity of another important area affected in Alzheimer's disease (AD), the frontal cortex, was also …
Dissociations between cognitive and motor effects of psychostimulants and atomoxetine in hyperactive DAT-KO mice.
Del'Guidice T, Lemasson M, Etiévant A, Manta S, Magno LA, Escoffier G, Roman FS, Beaulieu JM. Del'Guidice T, et al. Among authors: roman fs. Psychopharmacology (Berl). 2014 Jan;231(1):109-22. doi: 10.1007/s00213-013-3212-8. Epub 2013 Aug 3. Psychopharmacology (Berl). 2014. PMID: 23912772
METHODS: We used a recently developed behavioral apparatus, the automated H-maze. The H-maze involves the consecutive learning of three different rules: delayed alternation, nonalternation, and reversal tasks. ...CONCLUSIONS: Taken together, these data …
METHODS: We used a recently developed behavioral apparatus, the automated H-maze. The H-maze involves the consec …
Evidence for early cognitive impairment related to frontal cortex in the 5XFAD mouse model of Alzheimer's disease.
Girard SD, Baranger K, Gauthier C, Jacquet M, Bernard A, Escoffier G, Marchetti E, Khrestchatisky M, Rivera S, Roman FS. Girard SD, et al. Among authors: roman fs. J Alzheimers Dis. 2013;33(3):781-96. doi: 10.3233/JAD-2012-120982. J Alzheimers Dis. 2013. PMID: 23042214
We compared frontal performance of 2-, 4-, and 6-month-old 5XFAD mice with their wild-type littermates using a newly developed automated device, the olfactory H-maze, in which mice have to discover three different rules consecutively according to the delayed reactio …
We compared frontal performance of 2-, 4-, and 6-month-old 5XFAD mice with their wild-type littermates using a newly developed automated dev …
Stimulation of 5-HT2C receptors improves cognitive deficits induced by human tryptophan hydroxylase 2 loss of function mutation.
Del'Guidice T, Lemay F, Lemasson M, Levasseur-Moreau J, Manta S, Etievant A, Escoffier G, Doré FY, Roman FS, Beaulieu JM. Del'Guidice T, et al. Among authors: roman fs. Neuropsychopharmacology. 2014 Apr;39(5):1125-34. doi: 10.1038/npp.2013.313. Epub 2013 Nov 7. Neuropsychopharmacology. 2014. PMID: 24196946 Free PMC article.
We applied a recently developed behavioral assay, the automated H-maze, to study cognitive functions in Tph2-KI mice. This assay involves the consecutive discovery of three different rules: a delayed alternation task, a non-alternation task, and a delayed reversal t …
We applied a recently developed behavioral assay, the automated H-maze, to study cognitive functions in Tph2-KI mice. This ass …