Romerio A - Search Results

1

Increasing the Chemical Variety of Small-Molecule-Based TLR4 Modulators: An Overview.

Romerio A, Peri F. Romerio A, et al. Front Immunol. 2020 Jul 10;11:1210. doi: 10.3389/fimmu.2020.01210. eCollection 2020. Front Immunol. 2020. PMID: 32765484 Free PMC article. Review.

2

Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and In Vivo Activity.

Facchini FA, Minotti A, Luraghi A, Romerio A, Gotri N, Matamoros-Recio A, Iannucci A, Palmer C, Wang G, Ingram R, Martin-Santamaria S, Pirianov G, De Andrea M, Valvano MA, Peri F. Facchini FA, et al. Among authors: romerio a. J Med Chem. 2021 Aug 26;64(16):12261-12272. doi: 10.1021/acs.jmedchem.1c00896. Epub 2021 Aug 12. J Med Chem. 2021. PMID: 34382796 Free PMC article.

3

Highly Selective SERCA2a Activators: Preclinical Development of a Congeneric Group of First-in-Class Drug Leads against Heart Failure.

Luraghi A, Ferrandi M, Barassi P, Arici M, Hsu SC, Torre E, Ronchi C, Romerio A, Chang GJ, Ferrari P, Bianchi G, Zaza A, Rocchetti M, Peri F. Luraghi A, et al. Among authors: romerio a. J Med Chem. 2022 May 26;65(10):7324-7333. doi: 10.1021/acs.jmedchem.2c00347. Epub 2022 May 17. J Med Chem. 2022. PMID: 35580334 Free PMC article.

4

New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants.

Romerio A, Gotri N, Franco AR, Artusa V, Shaik MM, Pasco ST, Atxabal U, Matamoros-Recio A, Mínguez-Toral M, Zalamea JD, Franconetti A, Abrescia NGA, Jimenez-Barbero J, Anguita J, Martín-Santamaría S, Peri F. Romerio A, et al. J Med Chem. 2023 Feb 23;66(4):3010-3029. doi: 10.1021/acs.jmedchem.2c01998. Epub 2023 Feb 2. J Med Chem. 2023. PMID: 36728697 Free PMC article.

5

Overcoming Challenges in Chemical Glycosylation to Achieve Innovative Vaccine Adjuvants Possessing Enhanced TLR4 Activity.

Romerio A, Franco AR, Shadrick M, Shaik MM, Artusa V, Italia A, Lami F, Demchenko AV, Peri F. Romerio A, et al. ACS Omega. 2023 Sep 18;8(39):36412-36417. doi: 10.1021/acsomega.3c05363. eCollection 2023 Oct 3. ACS Omega. 2023. PMID: 37810727 Free PMC article.

6

Cleaner synthesis of preclinically validated vaccine adjuvants.

Romerio A, Peri F. Romerio A, et al. Front Chem. 2023 Nov 2;11:1252996. doi: 10.3389/fchem.2023.1252996. eCollection 2023. Front Chem. 2023. PMID: 38025058 Free PMC article.

7

Novel TLR4-Activating Vaccine Adjuvant Enhances the Production of Enterococcus faecium-binding Antibodies.

Franco AR, Sadones O, Romerio A, Artusa V, Shaik MM, Pasco ST, Italia A, D'Amato S, Anguita J, Huebner J, Romero-Saavedra F, Peri F. Franco AR, et al. Among authors: romerio a. J Med Chem. 2024 Apr 11;67(7):5603-5616. doi: 10.1021/acs.jmedchem.3c02215. Epub 2024 Mar 21. J Med Chem. 2024. PMID: 38513080

8

Vibrational spectroscopy coupled with machine learning sheds light on the cellular effects induced by rationally designed TLR4 agonists.

Ami D, Franco AR, Artusa V, Romerio A, Shaik MM, Italia A, Anguita J, Pasco S, Mereghetti P, Peri F, Natalello A. Ami D, et al. Among authors: romerio a. Talanta. 2024 Aug 1;275:126104. doi: 10.1016/j.talanta.2024.126104. Epub 2024 Apr 17. Talanta. 2024. PMID: 38677166 Free article.

9

Development of a New Vaccine Adjuvant System Based on the Combination of the Synthetic TLR4 Agonist FP20 and a Synthetic QS-21 Variant.

Shaik MM, Pasco S, Romerio A, Pifferi C, Sesana S, Re F, Bezuidenhout CX, Bracco S, Fernandez-Tejada A, Anguita J, Peri F. Shaik MM, et al. Among authors: romerio a. J Med Chem. 2024 Dec 26;67(24):22254-22262. doi: 10.1021/acs.jmedchem.4c02392. Epub 2024 Dec 8. J Med Chem. 2024. PMID: 39645607 Free PMC article.

10

Preclinical development of the TLR4 antagonist FP12 as a drug lead targeting the HMGB1/MD-2/TLR4 axis in lethal influenza infection.

Shirey KA, Romerio A, Shaik MM, Leake DS, Palmer C, Skupinska N, Paton J, Pirianov G, Blanco JC, Vogel SN, Peri F. Shirey KA, et al. Among authors: romerio a. Innate Immun. 2025 Jan-Dec;31:17534259241313201. doi: 10.1177/17534259241313201. Innate Immun. 2025. PMID: 40033742 Free PMC article.

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