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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase.
Harding HP, Zhang Y, Ron D. Harding HP, et al. Among authors: ron d. Nature. 1999 Jan 21;397(6716):271-4. doi: 10.1038/16729. Nature. 1999. PMID: 9930704
Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2.
Costa-Mattioli M, Gobert D, Harding H, Herdy B, Azzi M, Bruno M, Bidinosti M, Ben Mamou C, Marcinkiewicz E, Yoshida M, Imataka H, Cuello AC, Seidah N, Sossin W, Lacaille JC, Ron D, Nader K, Sonenberg N. Costa-Mattioli M, et al. Among authors: ron d. Nature. 2005 Aug 25;436(7054):1166-73. doi: 10.1038/nature03897. Nature. 2005. PMID: 16121183 Free PMC article.
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability.
Ding WX, Ni HM, Gao W, Yoshimori T, Stolz DB, Ron D, Yin XM. Ding WX, et al. Among authors: ron d. Am J Pathol. 2007 Aug;171(2):513-24. doi: 10.2353/ajpath.2007.070188. Epub 2007 Jul 9. Am J Pathol. 2007. PMID: 17620365 Free PMC article.
The endoplasmic reticulum stress response in the pancreatic β-cell.
Volchuk A, Ron D. Volchuk A, et al. Among authors: ron d. Diabetes Obes Metab. 2010 Oct;12 Suppl 2:48-57. doi: 10.1111/j.1463-1326.2010.01271.x. Diabetes Obes Metab. 2010. PMID: 21029300 Review.
ERO1-independent production of H2O2 within the endoplasmic reticulum fuels Prdx4-mediated oxidative protein folding.
Konno T, Pinho Melo E, Lopes C, Mehmeti I, Lenzen S, Ron D, Avezov E. Konno T, et al. Among authors: ron d. J Cell Biol. 2015 Oct 26;211(2):253-9. doi: 10.1083/jcb.201506123. J Cell Biol. 2015. PMID: 26504166 Free PMC article.
Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants.
Tsunoda S, Avezov E, Zyryanova A, Konno T, Mendes-Silva L, Pinho Melo E, Harding HP, Ron D. Tsunoda S, et al. Among authors: ron d. Elife. 2014 Jul 29;3:e03421. doi: 10.7554/eLife.03421. Elife. 2014. PMID: 25073928 Free PMC article.
AMPylation matches BiP activity to client protein load in the endoplasmic reticulum.
Preissler S, Rato C, Chen R, Antrobus R, Ding S, Fearnley IM, Ron D. Preissler S, et al. Among authors: ron d. Elife. 2015 Dec 17;4:e12621. doi: 10.7554/eLife.12621. Elife. 2015. PMID: 26673894 Free PMC article.
Single particle trajectories reveal active endoplasmic reticulum luminal flow.
Holcman D, Parutto P, Chambers JE, Fantham M, Young LJ, Marciniak SJ, Kaminski CF, Ron D, Avezov E. Holcman D, et al. Among authors: ron d. Nat Cell Biol. 2018 Oct;20(10):1118-1125. doi: 10.1038/s41556-018-0192-2. Epub 2018 Sep 17. Nat Cell Biol. 2018. PMID: 30224760 Free PMC article.
MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP.
Yan Y, Rato C, Rohland L, Preissler S, Ron D. Yan Y, et al. Among authors: ron d. Nat Commun. 2019 Feb 1;10(1):541. doi: 10.1038/s41467-019-08450-4. Nat Commun. 2019. PMID: 30710085 Free PMC article.
Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells.
Jousse C, Oyadomari S, Novoa I, Lu P, Zhang Y, Harding HP, Ron D. Jousse C, et al. Among authors: ron d. J Cell Biol. 2003 Nov 24;163(4):767-75. doi: 10.1083/jcb.200308075. J Cell Biol. 2003. PMID: 14638860 Free PMC article.
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