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The genetic relationship between individual differences in social and nonsocial behaviours characteristic of autism.
Ronald A, Happé F, Plomin R. Ronald A, et al. Dev Sci. 2005 Sep;8(5):444-58. doi: 10.1111/j.1467-7687.2005.00433.x. Dev Sci. 2005. PMID: 16048517
Parent and teacher data on social and nonsocial behaviours were obtained from a community sample of >3000 7-year-old twin pairs. ...
Parent and teacher data on social and nonsocial behaviours were obtained from a community sample of >3000 7-year-old twin pairs. . …
Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP-25, and 5HT1B.
Mill J, Xu X, Ronald A, Curran S, Price T, Knight J, Craig I, Sham P, Plomin R, Asherson P. Mill J, et al. Am J Med Genet B Neuropsychiatr Genet. 2005 Feb 5;133B(1):68-73. doi: 10.1002/ajmg.b.30107. Am J Med Genet B Neuropsychiatr Genet. 2005. PMID: 15578613
A consequence of this is that the genes associated with DSM-IV ADHD should also influence these underlying traits in non-affected individuals. ...We have genotyped five candidate markers in a population-based sample of male dizygous twin-pairs (n = 329 pairs). We fo
A consequence of this is that the genes associated with DSM-IV ADHD should also influence these underlying traits in non-affected ind
The etiology of behavior problems in 7-year-old twins: substantial genetic influence and negligible shared environmental influence for parent ratings and ratings by same and different teachers.
Saudino KJ, Ronald A, Plomin R. Saudino KJ, et al. J Abnorm Child Psychol. 2005 Feb;33(1):113-30. doi: 10.1007/s10802-005-0939-7. J Abnorm Child Psychol. 2005. PMID: 15759595
Genetic influences on the stability of attention-deficit/hyperactivity disorder symptoms from early to middle childhood.
Kuntsi J, Rijsdijk F, Ronald A, Asherson P, Plomin R. Kuntsi J, et al. Biol Psychiatry. 2005 Mar 15;57(6):647-54. doi: 10.1016/j.biopsych.2004.12.032. Biol Psychiatry. 2005. PMID: 15780852
METHODS: We report data from a large, population-based study of approximately 4,000 twin pairs, who have been followed up from early to middle childhood. ...
METHODS: We report data from a large, population-based study of approximately 4,000 twin pairs, who have been followed up from early …
Genetic research into autism.
Ronald A, Happé F, Plomin R. Ronald A, et al. Science. 2006 Feb 17;311(5763):952; author reply 952. doi: 10.1126/science.311.5763.952a. Science. 2006. PMID: 16484478 No abstract available.
Genetic heterogeneity between the three components of the autism spectrum: a twin study.
Ronald A, Happé F, Bolton P, Butcher LM, Price TS, Wheelwright S, Baron-Cohen S, Plomin R. Ronald A, et al. J Am Acad Child Adolesc Psychiatry. 2006 Jun;45(6):691-699. doi: 10.1097/01.chi.0000215325.13058.9d. J Am Acad Child Adolesc Psychiatry. 2006. PMID: 16721319
METHOD: Parents of 3,400 8-year-old twin pairs from the Twins Early Development Study completed the Childhood Asperger Syndrome Test, a screening instrument for autism spectrum symptoms in mainstream samples. ...RESULTS: High heritability was found for extreme autistic-lik …
METHOD: Parents of 3,400 8-year-old twin pairs from the Twins Early Development Study completed the Childhood Asperger Syndrome Test, a
Time to give up on a single explanation for autism.
Happé F, Ronald A, Plomin R. Happé F, et al. Nat Neurosci. 2006 Oct;9(10):1218-20. doi: 10.1038/nn1770. Nat Neurosci. 2006. PMID: 17001340 Review.
At the cognitive level, too, attempts at a single explanation for the symptoms of autism have failed. Implications for research and treatment are discussed....
At the cognitive level, too, attempts at a single explanation for the symptoms of autism have failed. Implications for research and t …
Phenotypic and genetic overlap between autistic traits at the extremes of the general population.
Ronald A, Happé F, Price TS, Baron-Cohen S, Plomin R. Ronald A, et al. J Am Acad Child Adolesc Psychiatry. 2006 Oct;45(10):1206-1214. doi: 10.1097/01.chi.0000230165.54117.41. J Am Acad Child Adolesc Psychiatry. 2006. PMID: 17003666
There was a degree of genetic overlap between them, but also substantial genetic specificity. CONCLUSIONS: This first twin study assessing the links between extreme individual autistic-like traits (SIs, CIs, and RRBIs) found that all are highly heritable but show modest ph …
There was a degree of genetic overlap between them, but also substantial genetic specificity. CONCLUSIONS: This first twin study asse …
Origins of individual differences in imitation: links with language, pretend play, and socially insightful behavior in two-year-old twins.
McEwen F, Happé F, Bolton P, Rijsdijk F, Ronald A, Dworzynski K, Plomin R. McEwen F, et al. Child Dev. 2007 Mar-Apr;78(2):474-92. doi: 10.1111/j.1467-8624.2007.01010.x. Child Dev. 2007. PMID: 17381785
A model that represented the covariance between the variables as being due to correlated latent genetic and environmental factors fitted the data well, with shared environmental factors influencing most of the covariance. ...
A model that represented the covariance between the variables as being due to correlated latent genetic and environmental factors fit
Aetiological relationship between language performance and autistic-like traits in childhood: a twin study.
Dworzynski K, Ronald A, Hayiou-Thomas M, Rijsdijk F, Happé F, Bolton PF, Plomin R. Dworzynski K, et al. Int J Lang Commun Disord. 2007 May-Jun;42(3):273-92. doi: 10.1080/13682820600939002. Int J Lang Commun Disord. 2007. PMID: 17514542
METHODS & PROCEDURES: Data came from a population-based twin sample (n = 6087 pairs) assessed prospectively at 2, 3, 4 and 8 years. ...
METHODS & PROCEDURES: Data came from a population-based twin sample (n = 6087 pairs) assessed prospectively at 2, 3, 4 and 8 year …
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