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Integrative biology of T cell activation.
Malissen B, Grégoire C, Malissen M, Roncagalli R. Malissen B, et al. Among authors: roncagalli r. Nat Immunol. 2014 Sep;15(9):790-7. doi: 10.1038/ni.2959. Nat Immunol. 2014. PMID: 25137453 Review.
Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor.
Roncagalli R, Taylor JE, Zhang S, Shi X, Chen R, Cruz-Munoz ME, Yin L, Latour S, Veillette A. Roncagalli R, et al. Nat Immunol. 2005 Oct;6(10):1002-10. doi: 10.1038/ni1242. Epub 2005 Aug 28. Nat Immunol. 2005. PMID: 16127454
The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes.
Mingueneau M, Sansoni A, Grégoire C, Roncagalli R, Aguado E, Weiss A, Malissen M, Malissen B. Mingueneau M, et al. Among authors: roncagalli r. Nat Immunol. 2008 May;9(5):522-32. doi: 10.1038/ni.1608. Epub 2008 Apr 13. Nat Immunol. 2008. PMID: 18408722
Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor.
Mingueneau M, Roncagalli R, Grégoire C, Kissenpfennig A, Miazek A, Archambaud C, Wang Y, Perrin P, Bertosio E, Sansoni A, Richelme S, Locksley RM, Aguado E, Malissen M, Malissen B. Mingueneau M, et al. Among authors: roncagalli r. Immunity. 2009 Aug 21;31(2):197-208. doi: 10.1016/j.immuni.2009.05.013. Epub 2009 Aug 13. Immunity. 2009. PMID: 19682930
Lymphoproliferative disorders involving T helper effector cells with defective LAT signalosomes.
Roncagalli R, Mingueneau M, Grégoire C, Langlet C, Malissen B, Malissen M. Roncagalli R, et al. Semin Immunopathol. 2010 Jun;32(2):117-25. doi: 10.1007/s00281-009-0195-y. Epub 2010 Jan 28. Semin Immunopathol. 2010. PMID: 20107804 Review.
LAT signaling pathology: an "autoimmune" condition without T cell self-reactivity.
Roncagalli R, Mingueneau M, Grégoire C, Malissen M, Malissen B. Roncagalli R, et al. Trends Immunol. 2010 Jul;31(7):253-9. doi: 10.1016/ Epub 2010 Jun 9. Trends Immunol. 2010. PMID: 20542732 Review.
The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.
Liang Y, Cucchetti M, Roncagalli R, Yokosuka T, Malzac A, Bertosio E, Imbert J, Nijman IJ, Suchanek M, Saito T, Wülfing C, Malissen B, Malissen M. Liang Y, et al. Among authors: roncagalli r. Nat Immunol. 2013 Aug;14(8):858-66. doi: 10.1038/ni.2634. Epub 2013 Jun 23. Nat Immunol. 2013. PMID: 23793062
Proteomic analysis of the SH2 domain-containing leukocyte protein of 76 kDa (SLP76) interactome in resting and activated primary mast cells [corrected].
Bounab Y, Hesse AM, Iannascoli B, Grieco L, Couté Y, Niarakis A, Roncagalli R, Lie E, Lam KP, Demangel C, Thieffry D, Garin J, Malissen B, Daëron M. Bounab Y, et al. Among authors: roncagalli r. Mol Cell Proteomics. 2013 Oct;12(10):2874-89. doi: 10.1074/mcp.M112.025908. Epub 2013 Jul 2. Mol Cell Proteomics. 2013. PMID: 23820730 Free PMC article.
Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub.
Roncagalli R, Hauri S, Fiore F, Liang Y, Chen Z, Sansoni A, Kanduri K, Joly R, Malzac A, Lähdesmäki H, Lahesmaa R, Yamasaki S, Saito T, Malissen M, Aebersold R, Gstaiger M, Malissen B. Roncagalli R, et al. Nat Immunol. 2014 Apr;15(4):384-392. doi: 10.1038/ni.2843. Epub 2014 Mar 2. Nat Immunol. 2014. PMID: 24584089 Free PMC article.
Computational modeling of the main signaling pathways involved in mast cell activation.
Niarakis A, Bounab Y, Grieco L, Roncagalli R, Hesse AM, Garin J, Malissen B, Daëron M, Thieffry D. Niarakis A, et al. Among authors: roncagalli r. Curr Top Microbiol Immunol. 2014;382:69-93. doi: 10.1007/978-3-319-07911-0_4. Curr Top Microbiol Immunol. 2014. PMID: 25116096 Review.
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