Comparison of free fructose and glucose to sucrose in the ability to cause fatty liver.
Eur J Nutr. 2010 Feb;49(1):1-9. doi: 10.1007/s00394-009-0042-x. Epub 2009 Jul 22.
Eur J Nutr. 2010.
Free PMC article.
Control rats were fed normal rat chow (C). All rats were pair fed and were followed for 4 months. After killing, blood chemistries and liver tissue were examined. RESULTS: Both FG-fed- and S-fed rats developed early features of metabolic syndrome when compared with C. In addition, both diets induced hepatic alterations, including variable increases in hepatic TG accumulation and fatty liver, an increase in uric acid content in the liver, as well as an increase in hepatic levels of monocyte chemoattractant protein-1 (MCP-1) and tumor necrosis factor-alpha (TNF-alpha) measured in liver homogenates. ...
Control rats were fed normal rat chow (C). All rats were pair fed and were followed for 4 months. After killing, blood chemistries an …