Roof R - Search Results

1

NIH research opportunities for the prevention and treatment for chronic conditions.

Elwood WN, Huss K, Morales DA, Norton JM, Riddle MW, Roof RA, Suls JM, Stoney CM, Bavendam TG, Kirkali Z. Elwood WN, et al. Among authors: roof ra. Transl Behav Med. 2018 May 23;8(3):509-514. doi: 10.1093/tbm/ibx085. Transl Behav Med. 2018. PMID: 29800410 Free PMC article.

2

Investigation of the binding and functional properties of extended length D3 dopamine receptor-selective antagonists.

Furman CA, Roof RA, Moritz AE, Miller BN, Doyle TB, Free RB, Banala AK, Paul NM, Kumar V, Sibley CD, Newman AH, Sibley DR. Furman CA, et al. Among authors: roof ra. Eur Neuropsychopharmacol. 2015 Sep;25(9):1448-61. doi: 10.1016/j.euroneuro.2014.11.013. Epub 2014 Nov 29. Eur Neuropsychopharmacol. 2015. PMID: 25583363 Free PMC article.

3

Modification of cocaine self-administration by buspirone (buspar®): potential involvement of D3 and D4 dopamine receptors.

Bergman J, Roof RA, Furman CA, Conroy JL, Mello NK, Sibley DR, Skolnick P. Bergman J, et al. Among authors: roof ra. Int J Neuropsychopharmacol. 2013 Mar;16(2):445-58. doi: 10.1017/S1461145712000661. Epub 2012 Jul 25. Int J Neuropsychopharmacol. 2013. PMID: 22827916 Free PMC article.

4

Phosphodiesterase 9A regulates central cGMP and modulates responses to cholinergic and monoaminergic perturbation in vivo.

Kleiman RJ, Chapin DS, Christoffersen C, Freeman J, Fonseca KR, Geoghegan KF, Grimwood S, Guanowsky V, Hajós M, Harms JF, Helal CJ, Hoffmann WE, Kocan GP, Majchrzak MJ, McGinnis D, McLean S, Menniti FS, Nelson F, Roof R, Schmidt AW, Seymour PA, Stephenson DT, Tingley FD, Vanase-Frawley M, Verhoest PR, Schmidt CJ. Kleiman RJ, et al. Among authors: roof r. J Pharmacol Exp Ther. 2012 May;341(2):396-409. doi: 10.1124/jpet.111.191353. Epub 2012 Feb 10. J Pharmacol Exp Ther. 2012. PMID: 22328573

5

N-(3-fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as selective dopamine D3 receptor ligands: critical role of the carboxamide linker for D3 receptor selectivity.

Banala AK, Levy BA, Khatri SS, Furman CA, Roof RA, Mishra Y, Griffin SA, Sibley DR, Luedtke RR, Newman AH. Banala AK, et al. Among authors: roof ra. J Med Chem. 2011 May 26;54(10):3581-94. doi: 10.1021/jm200288r. Epub 2011 May 2. J Med Chem. 2011. PMID: 21495689 Free PMC article.

6

Differential modulation of mu-opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Galpha subtype dependent.

Talbot JN, Roman DL, Clark MJ, Roof RA, Tesmer JJ, Neubig RR, Traynor JR. Talbot JN, et al. Among authors: roof ra. J Neurochem. 2010 Feb;112(4):1026-34. doi: 10.1111/j.1471-4159.2009.06519.x. Epub 2009 Nov 30. J Neurochem. 2010. PMID: 20002516 Free PMC article.

7

A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen.

Roof RA, Roman DL, Clements ST, Sobczyk-Kojiro K, Blazer LL, Ota S, Mosberg HI, Neubig RR. Roof RA, et al. BMC Pharmacol. 2009 May 22;9:9. doi: 10.1186/1471-2210-9-9. BMC Pharmacol. 2009. PMID: 19463173 Free PMC article.

8

Synthesis and SAR of tolylamine 5-HT6 antagonists.

Singer JM, Wilson MW, Johnson PD, Graham SR, Cooke LW, Roof RL, Boxer PA, Gold LH, Meltzer LT, Janssen A, Roush N, Campbell JE, Su TZ, Hurst SI, Stoner CL, Schwarz JB. Singer JM, et al. Among authors: roof rl. Bioorg Med Chem Lett. 2009 May 1;19(9):2409-12. doi: 10.1016/j.bmcl.2009.03.077. Epub 2009 Mar 25. Bioorg Med Chem Lett. 2009. PMID: 19346128

9

Identification and SAR around N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide, a selective alpha2C adrenergic receptor antagonist.

Patel SD, Habeski WM, Min H, Zhang J, Roof R, Snyder B, Bora G, Campbell B, Li C, Hidayetoglu D, Johnson DS, Chaudhry A, Charlton ME, Kablaoui NM. Patel SD, et al. Among authors: roof r. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5689-93. doi: 10.1016/j.bmcl.2008.08.055. Epub 2008 Aug 22. Bioorg Med Chem Lett. 2008. PMID: 18799310

10

Novel peptide ligands of RGS4 from a focused one-bead, one-compound library.

Roof RA, Sobczyk-Kojiro K, Turbiak AJ, Roman DL, Pogozheva ID, Blazer LL, Neubig RR, Mosberg HI. Roof RA, et al. Chem Biol Drug Des. 2008 Aug;72(2):111-9. doi: 10.1111/j.1747-0285.2008.00687.x. Epub 2008 Jul 15. Chem Biol Drug Des. 2008. PMID: 18637987 Free PMC article.

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