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Defective Lipid Droplet-Lysosome Interaction Causes Fatty Liver Disease as Evidenced by Human Mutations in TMEM199 and CCDC115.
Larsen LE, van den Boogert MAW, Rios-Ocampo WA, Jansen JC, Conlon D, Chong PLE, Levels JHM, Eilers RE, Sachdev VV, Zelcer N, Raabe T, He M, Hand NJ, Drenth JPH, Rader DJ, Stroes ESG, Lefeber DJ, Jonker JW, Holleboom AG. Larsen LE, et al. Among authors: eilers re. Cell Mol Gastroenterol Hepatol. 2022;13(2):583-597. doi: 10.1016/j.jcmgh.2021.09.013. Epub 2021 Oct 7. Cell Mol Gastroenterol Hepatol. 2022. PMID: 34626841 Free PMC article.
The chemotherapeutic drug doxorubicin does not exacerbate p16Ink4a-positive senescent cell accumulation and cardiometabolic disease development in young adult female LDLR-deficient mice.
Postmus AC, Kruit JK, Eilers RE, Havinga R, Koster MH, Johmura Y, Nakanishi M, van de Sluis B, Jonker JW. Postmus AC, et al. Among authors: eilers re. Toxicol Appl Pharmacol. 2023 Jun 1;468:116531. doi: 10.1016/j.taap.2023.116531. Epub 2023 Apr 23. Toxicol Appl Pharmacol. 2023. PMID: 37088304 Free article.
Loss of Early Growth Response Protein 1 in the Liver Leads to Hepatic Lipid Accumulation Driven by an Imbalance Between Fatty Acid β-Oxidation and Oxidative Phosphorylation.
Verzijl CRC, Struik D, Gerding A, Eilers RE, Thomas RE, Koster M, Langelaar-Makkinje M, Smit M, Huijkman N, Havinga R, Kloosterhuis N, Bloks VW, Wolters JC, de Boer JF, van de Sluis B, Bakker BM, Jonker JW. Verzijl CRC, et al. Among authors: eilers re. Gastro Hep Adv. 2026 Jan 19;5(4):100881. doi: 10.1016/j.gastha.2026.100881. eCollection 2026. Gastro Hep Adv. 2026. PMID: 41768523 Free PMC article.