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Mercury induces proliferation and reduces cell size in vascular smooth muscle cells through MAPK, oxidative stress and cyclooxygenase-2 pathways.
Aguado A, Galán M, Zhenyukh O, Wiggers GA, Roque FR, Redondo S, Peçanha F, Martín A, Fortuño A, Cachofeiro V, Tejerina T, Salaices M, Briones AM. Aguado A, et al. Among authors: roque fr. Toxicol Appl Pharmacol. 2013 Apr 15;268(2):188-200. doi: 10.1016/j.taap.2013.01.030. Epub 2013 Feb 13. Toxicol Appl Pharmacol. 2013. PMID: 23415682
Lysyl Oxidase Induces Vascular Oxidative Stress and Contributes to Arterial Stiffness and Abnormal Elastin Structure in Hypertension: Role of p38MAPK.
Martínez-Revelles S, García-Redondo AB, Avendaño MS, Varona S, Palao T, Orriols M, Roque FR, Fortuño A, Touyz RM, Martínez-González J, Salaices M, Rodríguez C, Briones AM. Martínez-Revelles S, et al. Among authors: roque fr. Antioxid Redox Signal. 2017 Sep 1;27(7):379-397. doi: 10.1089/ars.2016.6642. Epub 2017 Jan 30. Antioxid Redox Signal. 2017. PMID: 28010122 Free PMC article.
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