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Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: a 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens.
Alehagen U, Johansson P, Björnstedt M, Rosén A, Dahlström U. Alehagen U, et al. Among authors: rosen a. Int J Cardiol. 2013 Sep 1;167(5):1860-6. doi: 10.1016/j.ijcard.2012.04.156. Epub 2012 May 23. Int J Cardiol. 2013. PMID: 22626835 Clinical Trial.
METHODS: A 5-year prospective randomized double-blind placebo-controlled trial among Swedish citizens aged 70 to 88 was performed in 443 participants given combined supplementation of selenium and coenzyme Q10 or a placebo. ...RESULTS: During a follow up time …
METHODS: A 5-year prospective randomized double-blind placebo-controlled trial among Swedish citizens aged 70 to 88 was performed in …
Different expression levels of glycans on leukemic cells-a novel screening method with molecularly imprinted polymers (MIP) targeting sialic acid.
El-Schich Z, Abdullah M, Shinde S, Dizeyi N, Rosén A, Sellergren B, Wingren AG. El-Schich Z, et al. Among authors: rosen a. Tumour Biol. 2016 Oct;37(10):13763-13768. doi: 10.1007/s13277-016-5280-y. Epub 2016 Jul 31. Tumour Biol. 2016. PMID: 27476172 Free PMC article.
SA plays an important role for regulation of the innate immunity, function as markers of the cells and can be recognized by a variety of receptors. ...These results show that SA-MIP can be used as a plastic antibody for detection of SA using both flow cytometry and …
SA plays an important role for regulation of the innate immunity, function as markers of the cells and can be recognized by a variety …
A protein disulfide isomerase/thioredoxin-1 complex is physically attached to exofacial membrane tumor necrosis factor receptors: overexpression in chronic lymphocytic leukemia cells.
Söderberg A, Hossain A, Rosén A. Söderberg A, et al. Among authors: rosen a. Antioxid Redox Signal. 2013 Feb 1;18(4):363-75. doi: 10.1089/ars.2012.4789. Epub 2012 Aug 21. Antioxid Redox Signal. 2013. PMID: 22775451
Here, we investigated whether Trx1 and protein disulfide isomerase (PDI), a chaperone and Trx-family member, may interact with TNFRs. ...CONCLUSION: We describe here a new level of TNF regulation, in which membrane TNFRs are redox controlled at the exofacial surface …
Here, we investigated whether Trx1 and protein disulfide isomerase (PDI), a chaperone and Trx-family member, may interact with TNFRs. …
Positive MRI contrast enhancement in THP-1 cells with Gd2O3 nanoparticles.
Klasson A, Ahrén M, Hellqvist E, Söderlind F, Rosén A, Käll PO, Uvdal K, Engström M. Klasson A, et al. Among authors: rosen a. Contrast Media Mol Imaging. 2008 May-Jun;3(3):106-11. doi: 10.1002/cmmi.236. Contrast Media Mol Imaging. 2008. PMID: 18546094
In this study, nanoparticles of gadolinium oxide (Gd2O3) have been investigated for cell labeling and capacity to generate a positive contrast. ...A prominent difference in signal intensity was observed, indicating that Gd2O3 nanoparticles can be used as a po …
In this study, nanoparticles of gadolinium oxide (Gd2O3) have been investigated for cell labeling and capacity to generate a positive …
Elevated circulating levels of thioredoxin and stress in chronic heart failure.
Jekell A, Hossain A, Alehagen U, Dahlström U, Rosén A. Jekell A, et al. Among authors: rosen a. Eur J Heart Fail. 2004 Dec;6(7):883-90. doi: 10.1016/j.ejheart.2004.03.003. Eur J Heart Fail. 2004. PMID: 15556050
BACKGROUND: Chronic heart failure (CHF) is a complex syndrome, in which reactive oxygen species and inflammatory cytokines are important stressors that contribute to the pathogenesis. ...SUBJECTS: A case-control study was conducted including a consecutive sam …
BACKGROUND: Chronic heart failure (CHF) is a complex syndrome, in which reactive oxygen species and inflammatory cytokines are import …
Antigens in chronic lymphocytic leukemia--implications for cell origin and leukemogenesis.
Rosén A, Murray F, Evaldsson C, Rosenquist R. Rosén A, et al. Semin Cancer Biol. 2010 Dec;20(6):400-9. doi: 10.1016/j.semcancer.2010.09.004. Epub 2010 Sep 21. Semin Cancer Biol. 2010. PMID: 20863893 Review.
Herein we discuss how evidence first illustrated a link between certain B cell receptor (BCR) specificities and disease outcome and the subsequent large-scale IG analyses which revealed the extent of "stereotyped" BCRs in CLL. ...
Herein we discuss how evidence first illustrated a link between certain B cell receptor (BCR) specificities and disease outcome and t …
Differentiation-associated redox-regulation in human B cell lines from stem cell/pro-B to plasma cell.
Nilsson J, Söderberg O, Nilsson K, Rosén A. Nilsson J, et al. Among authors: rosen a. Immunol Lett. 2004 Jun 15;94(1-2):83-9. doi: 10.1016/j.imlet.2004.04.004. Immunol Lett. 2004. PMID: 15234539
Thioredoxin (Trx) is a key redox-regulating protein and oxidative stress sensor operating in synergy with Trx-reductase and protein disulfide isomerase (PDI). ...We found a significant congruence and co-variation of Trx and Bcl-2 levels in the B-lineage, with high e …
Thioredoxin (Trx) is a key redox-regulating protein and oxidative stress sensor operating in synergy with Trx-reductase and protein d …
Molecular characterization of neoplastic and normal "sister" lymphoblastoid B-cell lines from chronic lymphocytic leukemia.
Lanemo Myhrinder A, Hellqvist E, Bergh AC, Jansson M, Nilsson K, Hultman P, Jonasson J, Buhl AM, Bredo Pedersen L, Jurlander J, Klein E, Weit N, Herling M, Rosenquist R, Rosén A. Lanemo Myhrinder A, et al. Among authors: rosen a. Leuk Lymphoma. 2013 Aug;54(8):1769-79. doi: 10.3109/10428194.2013.764418. Epub 2013 Feb 25. Leuk Lymphoma. 2013. PMID: 23297799
We present here a comprehensive genotypic and phenotypic characterization of available CLL and normal B-cell-derived lymphoblastoid cell lines (LCLs) from the same individuals (n = 17). ...This panel of immortalized CLL-derived cell lines is a valuable reference rep …
We present here a comprehensive genotypic and phenotypic characterization of available CLL and normal B-cell-derived lymphoblastoid c …
Myelin protein zero is naturally processed in the B cells of monoclonal gammopathy of undetermined significance of immunoglobulin M isotype: aberrant triggering of a patient's T cells.
Hellqvist E, Kvarnström M, Söderberg A, Vrethem M, Ernerudh J, Rosén A. Hellqvist E, et al. Among authors: rosen a. Haematologica. 2010 Apr;95(4):627-36. doi: 10.3324/haematol.2009.015123. Epub 2009 Dec 16. Haematologica. 2010. PMID: 20015874 Free PMC article.
BACKGROUND: Monoclonal gammopathy of undetermined significance of immunoglobulin M isotype is a condition with clonally expanded B cells, recently suggested to have an infectious origin. ...DESIGN AND METHODS: We used a well-characterized monoclonal gammopathy of un …
BACKGROUND: Monoclonal gammopathy of undetermined significance of immunoglobulin M isotype is a condition with clonally expanded B ce …
Lymphoblastoid cell line with B1 cell characteristics established from a chronic lymphocytic leukemia clone by in vitro EBV infection.
Rosén A, Bergh AC, Gogok P, Evaldsson C, Myhrinder AL, Hellqvist E, Rasul A, Björkholm M, Jansson M, Mansouri L, Liu A, Teh BT, Rosenquist R, Klein E. Rosén A, et al. Oncoimmunology. 2012 Jan 1;1(1):18-27. doi: 10.4161/onci.1.1.18400. Oncoimmunology. 2012. PMID: 22720208 Free PMC article.
These genes may play a role in the development of the disease. LHX2 expression was shown in self-renewing multipotent hematopoietic stem cells, and LILRA4 codes for a receptor for bone marrow stromal cell antigen-2 that contributes to B cell development. ...Expressi …
These genes may play a role in the development of the disease. LHX2 expression was shown in self-renewing multipotent hematopoietic s …
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