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Karyotypic complexity of the NCI-60 drug-screening panel.
Roschke AV, Tonon G, Gehlhaus KS, McTyre N, Bussey KJ, Lababidi S, Scudiero DA, Weinstein JN, Kirsch IR. Roschke AV, et al. Cancer Res. 2003 Dec 15;63(24):8634-47. Cancer Res. 2003. PMID: 14695175
Chromosomal instability is associated with higher expression of genes implicated in epithelial-mesenchymal transition, cancer invasiveness, and metastasis and with lower expression of genes involved in cell cycle checkpoints, DNA repair, and chromatin maintenance.
Roschke AV, Glebov OK, Lababidi S, Gehlhaus KS, Weinstein JN, Kirsch IR. Roschke AV, et al. Neoplasia. 2008 Nov;10(11):1222-30. doi: 10.1593/neo.08682. Neoplasia. 2008. PMID: 18953431 Free PMC article.
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