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NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome.
Boute N, Gribouval O, Roselli S, Benessy F, Lee H, Fuchshuber A, Dahan K, Gubler MC, Niaudet P, Antignac C. Boute N, et al. Among authors: roselli s. Nat Genet. 2000 Apr;24(4):349-54. doi: 10.1038/74166. Nat Genet. 2000. PMID: 10742096
Early glomerular filtration defect and severe renal disease in podocin-deficient mice.
Roselli S, Heidet L, Sich M, Henger A, Kretzler M, Gubler MC, Antignac C. Roselli S, et al. Mol Cell Biol. 2004 Jan;24(2):550-60. doi: 10.1128/mcb.24.2.550-560.2004. Mol Cell Biol. 2004. PMID: 14701729 Free PMC article.
Podocin localizes in the kidney to the slit diaphragm area.
Roselli S, Gribouval O, Boute N, Sich M, Benessy F, AttiƩ T, Gubler MC, Antignac C. Roselli S, et al. Am J Pathol. 2002 Jan;160(1):131-9. doi: 10.1016/S0002-9440(10)64357-X. Am J Pathol. 2002. PMID: 11786407 Free PMC article.
Plasma membrane targeting of podocin through the classical exocytic pathway: effect of NPHS2 mutations.
Roselli S, Moutkine I, Gribouval O, Benmerah A, Antignac C. Roselli S, et al. Traffic. 2004 Jan;5(1):37-44. doi: 10.1046/j.1600-0854.2003.00148.x. Traffic. 2004. PMID: 14675423
[Characterization of the NPH2 gene, coding for the glomerular protein podocin, implicated in a familial form of cortico-resistant nephrotic syndrome transmitted as an autosomal recessive].
Boute N, Roselli S, Gribouval O, Niaudet P, Gubler MC, Antignac C. Boute N, et al. Among authors: roselli s. Nephrologie. 2002;23(1):35-6. Nephrologie. 2002. PMID: 11908478 French. No abstract available.
ProNGF correlates with Gleason score and is a potential driver of nerve infiltration in prostate cancer.
Pundavela J, Demont Y, Jobling P, Lincz LF, Roselli S, Thorne RF, Bond D, Bradshaw RA, Walker MM, Hondermarck H. Pundavela J, et al. Among authors: roselli s. Am J Pathol. 2014 Dec;184(12):3156-62. doi: 10.1016/j.ajpath.2014.08.009. Epub 2014 Oct 5. Am J Pathol. 2014. PMID: 25285721
Deletion of CD151 results in a strain-dependent glomerular disease due to severe alterations of the glomerular basement membrane.
Baleato RM, Guthrie PL, Gubler MC, Ashman LK, Roselli S. Baleato RM, et al. Among authors: roselli s. Am J Pathol. 2008 Oct;173(4):927-37. doi: 10.2353/ajpath.2008.071149. Epub 2008 Sep 11. Am J Pathol. 2008. PMID: 18787104 Free PMC article.
Functional importance of PP2A regulatory subunit loss in breast cancer.
Watt LF, Panicker N, Mannan A, Copeland B, Kahl RGS, Dun MD, Young B, Roselli S, Verrills NM. Watt LF, et al. Among authors: roselli s. Breast Cancer Res Treat. 2017 Nov;166(1):117-131. doi: 10.1007/s10549-017-4403-5. Epub 2017 Jul 25. Breast Cancer Res Treat. 2017. PMID: 28744751
ProNGF is a potential diagnostic biomarker for thyroid cancer.
Faulkner S, Roselli S, Demont Y, Pundavela J, Choquet G, Leissner P, Oldmeadow C, Attia J, Walker MM, Hondermarck H. Faulkner S, et al. Among authors: roselli s. Oncotarget. 2016 May 10;7(19):28488-97. doi: 10.18632/oncotarget.8652. Oncotarget. 2016. PMID: 27074571 Free PMC article.
Nerve fibers infiltrate the tumor microenvironment and are associated with nerve growth factor production and lymph node invasion in breast cancer.
Pundavela J, Roselli S, Faulkner S, Attia J, Scott RJ, Thorne RF, Forbes JF, Bradshaw RA, Walker MM, Jobling P, Hondermarck H. Pundavela J, et al. Among authors: roselli s. Mol Oncol. 2015 Oct;9(8):1626-35. doi: 10.1016/j.molonc.2015.05.001. Epub 2015 May 14. Mol Oncol. 2015. PMID: 26009480 Free PMC article.
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