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DNA methylation age is accelerated in alcohol dependence.
Rosen AD, Robertson KD, Hlady RA, Muench C, Lee J, Philibert R, Horvath S, Kaminsky ZA, Lohoff FW. Rosen AD, et al. Transl Psychiatry. 2018 Sep 5;8(1):182. doi: 10.1038/s41398-018-0233-4. Transl Psychiatry. 2018. PMID: 30185790 Free PMC article.
Genetic Association and Expression Analyses of the Phosphatidylinositol-4-Phosphate 5-Kinase (PIP5K1C) Gene in Alcohol Use Disorder-Relevance for Pain Signaling and Alcohol Use.
Lee JS, Sorcher JL, Rosen AD, Damadzic R, Sun H, Schwandt M, Heilig M, Kelly J, Mauro KL, Luo A, Rosoff D, Muench C, Jung J, Kaminsky ZA, Lohoff FW. Lee JS, et al. Among authors: rosen ad. Alcohol Clin Exp Res. 2018 Jun;42(6):1034-1043. doi: 10.1111/acer.13751. Epub 2018 May 9. Alcohol Clin Exp Res. 2018. PMID: 29667742 Free PMC article.
Methylomic profiling and replication implicates deregulation of PCSK9 in alcohol use disorder.
Lohoff FW, Sorcher JL, Rosen AD, Mauro KL, Fanelli RR, Momenan R, Hodgkinson CA, Vendruscolo LF, Koob GF, Schwandt M, George DT, Jones IS, Holmes A, Zhou Z, Xu MJ, Gao B, Sun H, Phillips MJ, Muench C, Kaminsky ZA. Lohoff FW, et al. Among authors: rosen ad. Mol Psychiatry. 2018 Sep;23(9):1900-1910. doi: 10.1038/mp.2017.168. Epub 2017 Aug 29. Mol Psychiatry. 2018. PMID: 28848234 Free PMC article.
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