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Effect of skeletal muscle Na(+) channel delivered via a cell platform on cardiac conduction and arrhythmia induction.
Boink GJ, Lu J, Driessen HE, Duan L, Sosunov EA, Anyukhovsky EP, Shlapakova IN, Lau DH, Rosen TS, Danilo P, Jia Z, Ozgen N, Bobkov Y, Guo Y, Brink PR, Kryukova Y, Robinson RB, Entcheva E, Cohen IS, Rosen MR. Boink GJ, et al. Among authors: rosen ts. Circ Arrhythm Electrophysiol. 2012 Aug 1;5(4):831-40. doi: 10.1161/CIRCEP.111.969907. Epub 2012 Jun 21. Circ Arrhythm Electrophysiol. 2012. PMID: 22722661 Free PMC article.
Epicardial border zone overexpression of skeletal muscle sodium channel SkM1 normalizes activation, preserves conduction, and suppresses ventricular arrhythmia: an in silico, in vivo, in vitro study.
Lau DH, Clausen C, Sosunov EA, Shlapakova IN, Anyukhovsky EP, Danilo P Jr, Rosen TS, Kelly C, Duffy HS, Szabolcs MJ, Chen M, Robinson RB, Lu J, Kumari S, Cohen IS, Rosen MR. Lau DH, et al. Among authors: rosen ts, rosen mr. Circulation. 2009 Jan 6;119(1):19-27. doi: 10.1161/CIRCULATIONAHA.108.809301. Epub 2008 Dec 22. Circulation. 2009. PMID: 19103989 Free PMC article.
SkM1 and Cx32 improve conduction in canine myocardial infarcts yet only SkM1 is antiarrhythmic.
Boink GJ, Lau DH, Shlapakova IN, Sosunov EA, Anyukhovsky EP, Driessen HE, Dun W, Chen M, Danilo P Jr, Rosen TS, Őzgen N, Duffy HS, Kryukova Y, Boyden PA, Robinson RB, Brink PR, Cohen IS, Rosen MR. Boink GJ, et al. Among authors: rosen ts. Cardiovasc Res. 2012 Jun 1;94(3):450-9. doi: 10.1093/cvr/cvs107. Epub 2012 Feb 27. Cardiovasc Res. 2012. PMID: 22374989 Free PMC article.
Atrial gradient as a potential predictor of atrial fibrillation.
Chandra P, Rosen TS, Herweg B, Plotnikov AN, Danilo P Jr, Rosen MR. Chandra P, et al. Among authors: rosen ts, rosen mr. Heart Rhythm. 2005 Apr;2(4):404-10. doi: 10.1016/j.hrthm.2004.12.027. Heart Rhythm. 2005. PMID: 15851344
Ability to induce atrial fibrillation in the peri-operative period is associated with phosphorylation-dependent inhibition of TWIK protein-related acid-sensitive potassium channel 1 (TASK-1).
Harleton E, Besana A, Comas GM, Danilo P Jr, Rosen TS, Argenziano M, Rosen MR, Robinson RB, Feinmark SJ. Harleton E, et al. Among authors: rosen ts. J Biol Chem. 2013 Jan 25;288(4):2829-38. doi: 10.1074/jbc.M112.404095. Epub 2012 Dec 10. J Biol Chem. 2013. PMID: 23229553 Free PMC article.
49 results