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Islet Neogenesis Associated Protein (INGAP) induces the differentiation of an adult human pancreatic ductal cell line into insulin-expressing cells through stepwise activation of key transcription factors for embryonic beta cell development.
Assouline-Thomas B, Ellis D, Petropavlovskaia M, Makhlin J, Ding J, Rosenberg L. Assouline-Thomas B, et al. Among authors: rosenberg l. Differentiation. 2015 Nov-Dec;90(4-5):77-90. doi: 10.1016/j.diff.2015.10.008. Epub 2015 Nov 11. Differentiation. 2015. PMID: 26558987
{beta}-Cell mass dynamics and islet cell plasticity in human type 2 diabetes.
Hanley SC, Austin E, Assouline-Thomas B, Kapeluto J, Blaichman J, Moosavi M, Petropavlovskaia M, Rosenberg L. Hanley SC, et al. Among authors: rosenberg l. Endocrinology. 2010 Apr;151(4):1462-72. doi: 10.1210/en.2009-1277. Epub 2010 Feb 22. Endocrinology. 2010. PMID: 20176718
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