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Plasmodium falciparum: inhibitors of lysosomal cysteine proteinases inhibit a trophozoite proteinase and block parasite development.
Rosenthal PJ, McKerrow JH, Rasnick D, Leech JH. Rosenthal PJ, et al. Mol Biochem Parasitol. 1989 Jun 15;35(2):177-83. doi: 10.1016/0166-6851(89)90120-5. Mol Biochem Parasitol. 1989. PMID: 2671722
Characterization of a Plasmodium vivax cysteine proteinase gene identifies uniquely conserved amino acids that may mediate the substrate specificity of malarial hemoglobinases.
Rosenthal PJ, Ring CS, Chen X, Cohen FE. Rosenthal PJ, et al. J Mol Biol. 1994 Aug 12;241(2):312-6. doi: 10.1006/jmbi.1994.1506. J Mol Biol. 1994. PMID: 8057374
Inhibition of a Plasmodium vinckei cysteine proteinase cures murine malaria.
Rosenthal PJ, Lee GK, Smith RE. Rosenthal PJ, et al. J Clin Invest. 1993 Mar;91(3):1052-6. doi: 10.1172/JCI116262. J Clin Invest. 1993. PMID: 8450035 Free PMC article.
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