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Variant-to-gene mapping identifies ARHGEF12 as a primary open-angle glaucoma effector gene operating within retinal ganglion cells.
Vrathasha V, Pahl MC, Pippin JA, Nikonov S, He J, Halimitabrizi M, Moksha L, Salowe R, Edziah AA, Bradford Y, Zhu Y, Gudiseva HV, Chavali VRM, da Costa BL, Berry AM, Quinn PMJ, Cui QN, Miller-Ellis E, Sankar PS, Ross AG, Addis V, Verma SS, Wells AD, Grant SFA, O'Brien JM. Vrathasha V, et al. Among authors: ross ag. bioRxiv [Preprint]. 2026 Mar 27:2026.02.20.707051. doi: 10.64898/2026.02.20.707051. bioRxiv. 2026. PMID: 41929112 Free PMC article. Preprint.
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