Rostami-Hodjegan A - Search Results

1

Cytochrome p450 turnover: regulation of synthesis and degradation, methods for determining rates, and implications for the prediction of drug interactions.

Yang J, Liao M, Shou M, Jamei M, Yeo KR, Tucker GT, Rostami-Hodjegan A. Yang J, et al. Curr Drug Metab. 2008 Jun;9(5):384-94. doi: 10.2174/138920008784746382. Curr Drug Metab. 2008. PMID: 18537575 Review.

2

Determination of drug-metabolizing enzyme activity in vivo: pharmacokinetic and statistical issues.

Tucker GT, Rostami-Hodjegan A, Jackson PR. Tucker GT, et al. Xenobiotica. 1998 Dec;28(12):1255-73. doi: 10.1080/004982598238895. Xenobiotica. 1998. PMID: 9890160 Review. No abstract available.

3

The 1'-hydroxylation of Rac-bufuralol by rat brain microsomes.

Coleman T, Spellman EF, Rostami-Hodjegan A, Lennard MS, Tucker GT. Coleman T, et al. Drug Metab Dispos. 2000 Sep;28(9):1094-9. Drug Metab Dispos. 2000. PMID: 10950855

4

Analysis of solvent central nervous system toxicity and ethanol interactions using a human population physiologically based kinetic and dynamic model.

MacDonald AJ, Rostami-Hodjegan A, Tucker GT, Linkens DA. MacDonald AJ, et al. Regul Toxicol Pharmacol. 2002 Apr;35(2 Pt 1):165-76. doi: 10.1006/rtph.2001.1507. Regul Toxicol Pharmacol. 2002. PMID: 12052002

5

Inter-individual variability in levels of human microsomal protein and hepatocellularity per gram of liver.

Wilson ZE, Rostami-Hodjegan A, Burn JL, Tooley A, Boyle J, Ellis SW, Tucker GT. Wilson ZE, et al. Br J Clin Pharmacol. 2003 Oct;56(4):433-40. doi: 10.1046/j.1365-2125.2003.01881.x. Br J Clin Pharmacol. 2003. PMID: 12968989 Free PMC article.

6

The effects of dose staggering on metabolic drug-drug interactions.

Yang J, Kjellsson M, Rostami-Hodjegan A, Tucker GT. Yang J, et al. Eur J Pharm Sci. 2003 Oct;20(2):223-32. doi: 10.1016/s0928-0987(03)00200-8. Eur J Pharm Sci. 2003. PMID: 14550889

7

Predicting drug clearance from recombinantly expressed CYPs: intersystem extrapolation factors.

Proctor NJ, Tucker GT, Rostami-Hodjegan A. Proctor NJ, et al. Xenobiotica. 2004 Feb;34(2):151-78. doi: 10.1080/00498250310001646353. Xenobiotica. 2004. PMID: 14985145

8

Mechanism-based inactivation of CYP2D6 by methylenedioxymethamphetamine.

Heydari A, Yeo KR, Lennard MS, Ellis SW, Tucker GT, Rostami-Hodjegan A. Heydari A, et al. Drug Metab Dispos. 2004 Nov;32(11):1213-7. doi: 10.1124/dmd.104.001180. Epub 2004 Aug 24. Drug Metab Dispos. 2004. PMID: 15328252

9

Kinetic values for mechanism-based enzyme inhibition: assessing the bias introduced by the conventional experimental protocol.

Yang J, Jamei M, Yeo KR, Tucker GT, Rostami-Hodjegan A. Yang J, et al. Eur J Pharm Sci. 2005 Nov;26(3-4):334-40. doi: 10.1016/j.ejps.2005.07.005. Eur J Pharm Sci. 2005. PMID: 16137870

10

Changes in liver volume from birth to adulthood: a meta-analysis.

Johnson TN, Tucker GT, Tanner MS, Rostami-Hodjegan A. Johnson TN, et al. Liver Transpl. 2005 Dec;11(12):1481-93. doi: 10.1002/lt.20519. Liver Transpl. 2005. PMID: 16315293

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