Rostami-Hodjegan A - Search Results

1

A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and genetics: A tale of 'bottom-up' vs 'top-down' recognition of covariates.

Jamei M, Dickinson GL, Rostami-Hodjegan A. Jamei M, et al. Drug Metab Pharmacokinet. 2009;24(1):53-75. doi: 10.2133/dmpk.24.53. Drug Metab Pharmacokinet. 2009. PMID: 19252336 Free article. Review.

2

Sensitivity of indirect metrics for assessing "rate" in bioequivalence studies--moving the "goalposts" or changing the "game".

Rostami-Hodjegan A, Jackson PR, Tucker GT. Rostami-Hodjegan A, et al. J Pharm Sci. 1994 Nov;83(11):1554-7. doi: 10.1002/jps.2600831107. J Pharm Sci. 1994. PMID: 7891273

3

Analysis of solvent central nervous system toxicity and ethanol interactions using a human population physiologically based kinetic and dynamic model.

MacDonald AJ, Rostami-Hodjegan A, Tucker GT, Linkens DA. MacDonald AJ, et al. Regul Toxicol Pharmacol. 2002 Apr;35(2 Pt 1):165-76. doi: 10.1006/rtph.2001.1507. Regul Toxicol Pharmacol. 2002. PMID: 12052002

4

A new rapidly absorbed paracetamol tablet containing sodium bicarbonate. I. A four-way crossover study to compare the concentration-time profile of paracetamol from the new paracetamol/sodium bicarbonate tablet and a conventional paracetamol tablet in fed and fasted volunteers.

Rostami-Hodjegan A, Shiran MR, Ayesh R, Grattan TJ, Burnett I, Darby-Dowman A, Tucker GT. Rostami-Hodjegan A, et al. Drug Dev Ind Pharm. 2002 May;28(5):523-31. doi: 10.1081/ddc-120003448. Drug Dev Ind Pharm. 2002. PMID: 12098841

5

A new rapidly absorbed paracetamol tablet containing sodium bicarbonate. II. Dissolution studies and in vitro/in vivo correlation.

Rostami-Hodjegan A, Shiran MR, Tucker GT, Conway BR, Irwin WJ, Shaw LR, Grattan TJ. Rostami-Hodjegan A, et al. Drug Dev Ind Pharm. 2002 May;28(5):533-43. doi: 10.1081/ddc-120003449. Drug Dev Ind Pharm. 2002. PMID: 12098842

6

An indirect response model of homocysteine suppression by betaine: optimising the dosage regimen of betaine in homocystinuria.

Matthews A, Johnson TN, Rostami-Hodjegan A, Chakrapani A, Wraith JE, Moat SJ, Bonham JR, Tucker GT. Matthews A, et al. Br J Clin Pharmacol. 2002 Aug;54(2):140-6. doi: 10.1046/j.1365-2125.2002.01620.x. Br J Clin Pharmacol. 2002. PMID: 12207633 Free PMC article.

7

Inter-individual variability in levels of human microsomal protein and hepatocellularity per gram of liver.

Wilson ZE, Rostami-Hodjegan A, Burn JL, Tooley A, Boyle J, Ellis SW, Tucker GT. Wilson ZE, et al. Br J Clin Pharmacol. 2003 Oct;56(4):433-40. doi: 10.1046/j.1365-2125.2003.01881.x. Br J Clin Pharmacol. 2003. PMID: 12968989 Free PMC article.

8

The effects of dose staggering on metabolic drug-drug interactions.

Yang J, Kjellsson M, Rostami-Hodjegan A, Tucker GT. Yang J, et al. Eur J Pharm Sci. 2003 Oct;20(2):223-32. doi: 10.1016/s0928-0987(03)00200-8. Eur J Pharm Sci. 2003. PMID: 14550889

9

Influence of dose, cigarette smoking, age, sex, and metabolic activity on plasma clozapine concentrations: a predictive model and nomograms to aid clozapine dose adjustment and to assess compliance in individual patients.

Rostami-Hodjegan A, Amin AM, Spencer EP, Lennard MS, Tucker GT, Flanagan RJ. Rostami-Hodjegan A, et al. J Clin Psychopharmacol. 2004 Feb;24(1):70-8. doi: 10.1097/01.jcp.0000106221.36344.4d. J Clin Psychopharmacol. 2004. PMID: 14709950

10

Predicting drug clearance from recombinantly expressed CYPs: intersystem extrapolation factors.

Proctor NJ, Tucker GT, Rostami-Hodjegan A. Proctor NJ, et al. Xenobiotica. 2004 Feb;34(2):151-78. doi: 10.1080/00498250310001646353. Xenobiotica. 2004. PMID: 14985145

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