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The following term was not found in PubMed: osvanis
Page 1
Showing results for osvanis tk
Search for Rosvanis TK instead (2 results)
KSHV-TK: thymidine kinase or tyrosine kinase?
Lagunoff M. Lagunoff M. EMBO J. 2015 Feb 12;34(4):427-9. doi: 10.15252/embj.201490843. Epub 2015 Jan 8. EMBO J. 2015. PMID: 25572594 Free PMC article.
The thymidine kinases (TK) of alphaherpesviruses phosphorylate nucleosides, allowing viral replication in non-dividing cells. ...KSHV-TK autophosphorylation of three SH2 domains leads to Crk binding and likely sequestration of Crk from focal adhesions. ...
The thymidine kinases (TK) of alphaherpesviruses phosphorylate nucleosides, allowing viral replication in non-dividing cells. ...KSHV …
Bifidobacterium infantis-Mediated Herpes Simplex Virus-TK/Ganciclovir Treatment Inhibits Cancer Metastasis in Mouse Model.
Wang C, Shen Y, Ma Y. Wang C, et al. Int J Mol Sci. 2023 Jul 21;24(14):11721. doi: 10.3390/ijms241411721. Int J Mol Sci. 2023. PMID: 37511481 Free PMC article.
Previous studies have found that Bifidobacterium infantis-mediated herpes simplex virus-TK/ganciclovir (BF-TK/GCV) reduces the expression of VEGF and CD146, implying tumor metastasis inhibition. ...In summary, BF-TK/GCV inhibited tumor metastasis, which deepe …
Previous studies have found that Bifidobacterium infantis-mediated herpes simplex virus-TK/ganciclovir (BF-TK/GCV) reduces the …
SmsB-SmsC machinery in Thermococcus kodakarensis functions as an archaeal scaffold mediating Fe-S cluster assembly.
Jin J-q, Sato T, Atomi H. Jin J-q, et al. Appl Environ Microbiol. 2025 Sep 17;91(9):e0143825. doi: 10.1128/aem.01438-25. Epub 2025 Aug 18. Appl Environ Microbiol. 2025. PMID: 40824041 Free PMC article.
The hyperthermophilic archaeon Thermococcus kodakarensis harbors candidate proteins for SmsB and SmsC (Tk-SmsB and Tk-SmsC) encoded by TK0730 and TK0731 genes, respectively. As Tk-SmsB is phylogenetically positioned in a clade distinct from the previously cha …
The hyperthermophilic archaeon Thermococcus kodakarensis harbors candidate proteins for SmsB and SmsC (Tk-SmsB and Tk-SmsC) en …
A review on research progress of transketolase.
Zhao J, Zhong CJ. Zhao J, et al. Neurosci Bull. 2009 Apr;25(2):94-9. doi: 10.1007/s12264-009-1113-y. Neurosci Bull. 2009. PMID: 19290028 Free PMC article. Review.
Both ThDP and bivalent cations are strictly needed for TK activation, just like that for all ThDP-dependent enzymes. TK exists in all organisms that have been investigated. ...Recent studies indicated TK as a novel role in the prevention and therapy of these …
Both ThDP and bivalent cations are strictly needed for TK activation, just like that for all ThDP-dependent enzymes. TK exists …
Food ingredient safety evaluation: Utility and relevance of toxicokinetic methods.
Kabadi SV, Zang Y, Fisher JW, Smith N, Whiteside C, Aungst J. Kabadi SV, et al. Toxicol Appl Pharmacol. 2019 Nov 1;382:114759. doi: 10.1016/j.taap.2019.114759. Epub 2019 Sep 12. Toxicol Appl Pharmacol. 2019. PMID: 31521730 Review.
The use of toxicokinetic (TK) data is becoming more prevalent in the evaluation of food ingredient safety as more TK information is being incorporated in safety data packages. ...Because of recent advancements, several approaches have been developed to improve sensi …
The use of toxicokinetic (TK) data is becoming more prevalent in the evaluation of food ingredient safety as more TK informati …
Activation of tyrosine kinases in cancer.
Vlahovic G, Crawford J. Vlahovic G, et al. Oncologist. 2003;8(6):531-8. doi: 10.1634/theoncologist.8-6-531. Oncologist. 2003. PMID: 14657531 Free article. Review.
STI571 (imatinib mesylate) inhibits the Bcr-Abl TK, blocks the growth of these leukemia cells, and induces apoptosis. STI571 also inhibits other TKs, including the receptor TK c-kit, which is expressed in gastrointestinal stromal tumors. As TK inhibitors beco …
STI571 (imatinib mesylate) inhibits the Bcr-Abl TK, blocks the growth of these leukemia cells, and induces apoptosis. STI571 also inh …
Traditional Chinese medicine method of tonifying kidney for hypertension: Clinical evidence and molecular mechanisms.
Wang Q, Lin J, Li C, Lin M, Zhang Q, Zhang X, Yao K. Wang Q, et al. Front Cardiovasc Med. 2022 Nov 16;9:1038480. doi: 10.3389/fcvm.2022.1038480. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 36465462 Free PMC article.
Data mining was used to screen the core herbs of the TK. Network pharmacology was used to predict the antihypertensive mechanism of TK core herbs. ...In addition, TK was safe and has no obvious adverse reactions. Data mining showed that the core herbs of T …
Data mining was used to screen the core herbs of the TK. Network pharmacology was used to predict the antihypertensive mechanism of …
Pathogenicity and immunogenicity of a gI/gE/TK/UL13-gene-deleted variant pseudorabies virus strain in swine.
Lv L, Liu X, Jiang C, Wang X, Cao M, Bai J, Jiang P. Lv L, et al. Vet Microbiol. 2021 Jul;258:109104. doi: 10.1016/j.vetmic.2021.109104. Epub 2021 May 8. Vet Microbiol. 2021. PMID: 34004569
ZJ01-deltagI/gE/TK/UL13 provided greater protective efficacy against challenge with PRV variant strain ZJ01 than did Bartha-K61 or ZJ01-deltagI/gE/TK. The pigs vaccinated with ZJ01-deltagI/gE/TK/UL13 excreted significantly less virus than those vaccinated wit …
ZJ01-deltagI/gE/TK/UL13 provided greater protective efficacy against challenge with PRV variant strain ZJ01 than did Bartha-K61 or ZJ …
Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases.
Oishi T, Ito M, Koizumi S, Horikawa M, Yamamoto T, Yamagishi S, Yamasaki T, Sameshima T, Suzuki T, Sugimura H, Namba H, Kurozumi K. Oishi T, et al. Mol Ther Methods Clin Dev. 2022 Jul 6;26:253-265. doi: 10.1016/j.omtm.2022.07.001. eCollection 2022 Sep 8. Mol Ther Methods Clin Dev. 2022. PMID: 35892087 Free PMC article.
We introduced the A168H mutant TK (TK(A168H)) into SHED to establish the therapeutic cells because of the latent toxicity of wild type. SHED expressing TK(A168H) (SHED-TK) exhibited chemotaxis to the conditioned medium of NSCLC and migrated toward impl …
We introduced the A168H mutant TK (TK(A168H)) into SHED to establish the therapeutic cells because of the latent toxicity of w …
Tat8-TK/GCV suicide gene therapy induces pancreatic tumor regression in vivo.
Cascante A, Huch M, Rodríguez LG, González JR, Costantini L, Fillat C. Cascante A, et al. Hum Gene Ther. 2005 Dec;16(12):1377-88. doi: 10.1089/hum.2005.16.1377. Hum Gene Ther. 2005. PMID: 16390269
We demonstrate that Tat8-TK protein is released from the intracellular compartment of Tat8-TK-expressing cells to the extracellular medium after GCV treatment. ...When moderate doses of GCV were administered, the overall reduction in tumor growth was statistically s …
We demonstrate that Tat8-TK protein is released from the intracellular compartment of Tat8-TK-expressing cells to the extracel …
25,092 results
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