Roth MG - Search Results

1

Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer.

Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, De Brabander J, Komurov K, Toombs JE, Wei S, Peyton M, Williams N, Gazdar AF, Posner BA, Brekken RA, Sood AK, Deberardinis RJ, Roth MG, Minna JD, White MA. Kim HS, et al. Among authors: roth mg. Cell. 2013 Oct 24;155(3):552-66. doi: 10.1016/j.cell.2013.09.041. Epub 2013 Oct 24. Cell. 2013. PMID: 24243015 Free PMC article.

2

Salicylihalamide A inhibits the V0 sector of the V-ATPase through a mechanism distinct from bafilomycin A1.

Xie XS, Padron D, Liao X, Wang J, Roth MG, De Brabander JK. Xie XS, et al. Among authors: roth mg. J Biol Chem. 2004 May 7;279(19):19755-63. doi: 10.1074/jbc.M313796200. Epub 2004 Mar 3. J Biol Chem. 2004. PMID: 14998996 Free article.

3

A missense mutation in Caenorhabditis elegans prohibitin 2 confers an atypical multidrug resistance.

Zubovych I, Doundoulakis T, Harran PG, Roth MG. Zubovych I, et al. Among authors: roth mg. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15523-8. doi: 10.1073/pnas.0607338103. Epub 2006 Oct 10. Proc Natl Acad Sci U S A. 2006. PMID: 17032754 Free PMC article.

4

Synthetic lethal screen identification of chemosensitizer loci in cancer cells.

Whitehurst AW, Bodemann BO, Cardenas J, Ferguson D, Girard L, Peyton M, Minna JD, Michnoff C, Hao W, Roth MG, Xie XJ, White MA. Whitehurst AW, et al. Among authors: roth mg. Nature. 2007 Apr 12;446(7137):815-9. doi: 10.1038/nature05697. Nature. 2007. PMID: 17429401

5

Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalized.

Padrón D, Sato M, Shay JW, Gazdar AF, Minna JD, Roth MG. Padrón D, et al. Among authors: roth mg. Cancer Res. 2007 Aug 15;67(16):7695-702. doi: 10.1158/0008-5472.CAN-07-0484. Cancer Res. 2007. PMID: 17699773 Free PMC article.

6

Evaluating the potential of vacuolar ATPase inhibitors as anticancer agents and multigram synthesis of the potent salicylihalamide analog saliphenylhalamide.

Lebreton S, Jaunbergs J, Roth MG, Ferguson DA, De Brabander JK. Lebreton S, et al. Among authors: roth mg. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5879-83. doi: 10.1016/j.bmcl.2008.07.003. Epub 2008 Jul 5. Bioorg Med Chem Lett. 2008. PMID: 18657422 Free PMC article.

7

Targeting QseC signaling and virulence for antibiotic development.

Rasko DA, Moreira CG, Li de R, Reading NC, Ritchie JM, Waldor MK, Williams N, Taussig R, Wei S, Roth M, Hughes DT, Huntley JF, Fina MW, Falck JR, Sperandio V. Rasko DA, et al. Science. 2008 Aug 22;321(5892):1078-80. doi: 10.1126/science.1160354. Science. 2008. PMID: 18719281 Free PMC article.

8

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer.

Chen B, Dodge ME, Tang W, Lu J, Ma Z, Fan CW, Wei S, Hao W, Kilgore J, Williams NS, Roth MG, Amatruda JF, Chen C, Lum L. Chen B, et al. Among authors: roth mg. Nat Chem Biol. 2009 Feb;5(2):100-7. doi: 10.1038/nchembio.137. Epub 2009 Jan 4. Nat Chem Biol. 2009. PMID: 19125156 Free PMC article.

9

Mitochondrial dysfunction confers resistance to multiple drugs in Caenorhabditis elegans.

Zubovych IO, Straud S, Roth MG. Zubovych IO, et al. Among authors: roth mg. Mol Biol Cell. 2010 Mar 15;21(6):956-69. doi: 10.1091/mbc.e09-08-0673. Epub 2010 Jan 20. Mol Biol Cell. 2010. PMID: 20089839 Free PMC article.

10

Comprehensive mapping of the human kinome to epidermal growth factor receptor signaling.

Komurov K, Padron D, Cheng T, Roth M, Rosenblatt KP, White MA. Komurov K, et al. J Biol Chem. 2010 Jul 2;285(27):21134-42. doi: 10.1074/jbc.M110.137828. Epub 2010 Apr 26. J Biol Chem. 2010. PMID: 20421302 Free PMC article.

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