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A Novel Complete Autosomal-Recessive STAT1 LOF Variant Causes Immunodeficiency with Hemophagocytic Lymphohistiocytosis-Like Hyperinflammation.
Boehmer DFR, Koehler LM, Magg T, Metzger P, Rohlfs M, Ahlfeld J, Rack-Hoch A, Reiter K, Albert MH, Endres S, Rothenfusser S, Klein C, Koenig LM, Hauck F. Boehmer DFR, et al. Among authors: rothenfusser s. J Allergy Clin Immunol Pract. 2020 Oct;8(9):3102-3111. doi: 10.1016/j.jaip.2020.06.034. Epub 2020 Jun 27. J Allergy Clin Immunol Pract. 2020. PMID: 32603902 Free PMC article.
Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12.
Krug A, Towarowski A, Britsch S, Rothenfusser S, Hornung V, Bals R, Giese T, Engelmann H, Endres S, Krieg AM, Hartmann G. Krug A, et al. Among authors: rothenfusser s. Eur J Immunol. 2001 Oct;31(10):3026-37. doi: 10.1002/1521-4141(2001010)31:10<3026::aid-immu3026>3.0.co;2-h. Eur J Immunol. 2001. PMID: 11592079 Free article.
Plasmacytoid dendritic cells: the key to CpG.
Rothenfusser S, Tuma E, Endres S, Hartmann G. Rothenfusser S, et al. Hum Immunol. 2002 Dec;63(12):1111-9. doi: 10.1016/s0198-8859(02)00749-8. Hum Immunol. 2002. PMID: 12480254 Review.
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