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Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.
Aste-Amézaga M, Zhang N, Lineberger JE, Arnold BA, Toner TJ, Gu M, Huang L, Vitelli S, Vo KT, Haytko P, Zhao JZ, Baleydier F, L'Heureux S, Wang H, Gordon WR, Thoryk E, Andrawes MB, Tiyanont K, Stegmaier K, Roti G, Ross KN, Franlin LL, Wang H, Wang F, Chastain M, Bett AJ, Audoly LP, Aster JC, Blacklow SC, Huber HE. Aste-Amézaga M, et al. Among authors: roti g. PLoS One. 2010 Feb 8;5(2):e9094. doi: 10.1371/journal.pone.0009094. PLoS One. 2010. PMID: 20161710 Free PMC article.
Targeting NOTCH1 in hematopoietic malignancy.
Roti G, Stegmaier K. Roti G, et al. Crit Rev Oncog. 2011;16(1-2):103-15. doi: 10.1615/critrevoncog.v16.i1-2.100. Crit Rev Oncog. 2011. PMID: 22150311 Review.
New Approaches to Target T-ALL.
Roti G, Stegmaier K. Roti G, et al. Front Oncol. 2014 Jul 8;4:170. doi: 10.3389/fonc.2014.00170. eCollection 2014. Front Oncol. 2014. PMID: 25072021 Free PMC article. Review.
Identification of AML1-ETO modulators by chemical genomics.
Corsello SM, Roti G, Ross KN, Chow KT, Galinsky I, DeAngelo DJ, Stone RM, Kung AL, Golub TR, Stegmaier K. Corsello SM, et al. Among authors: roti g. Blood. 2009 Jun 11;113(24):6193-205. doi: 10.1182/blood-2008-07-166090. Epub 2009 Apr 17. Blood. 2009. PMID: 19377049 Free PMC article.
The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.
Banerji V, Frumm SM, Ross KN, Li LS, Schinzel AC, Hahn CK, Kakoza RM, Chow KT, Ross L, Alexe G, Tolliday N, Inguilizian H, Galinsky I, Stone RM, DeAngelo DJ, Roti G, Aster JC, Hahn WC, Kung AL, Stegmaier K. Banerji V, et al. Among authors: roti g. J Clin Invest. 2012 Mar;122(3):935-47. doi: 10.1172/JCI46465. Epub 2012 Feb 13. J Clin Invest. 2012. PMID: 22326953 Free PMC article.
Leukemia-specific delivery of mutant NOTCH1 targeted therapy.
Roti G, Qi J, Kitara S, Sanchez-Martin M, Saur Conway A, Varca AC, Su A, Wu L, Kung AL, Ferrando AA, Bradner JE, Stegmaier K. Roti G, et al. J Exp Med. 2018 Jan 2;215(1):197-216. doi: 10.1084/jem.20151778. Epub 2017 Nov 20. J Exp Med. 2018. PMID: 29158376 Free PMC article.
Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.
Frumm SM, Fan ZP, Ross KN, Duvall JR, Gupta S, VerPlank L, Suh BC, Holson E, Wagner FF, Smith WB, Paranal RM, Bassil CF, Qi J, Roti G, Kung AL, Bradner JE, Tolliday N, Stegmaier K. Frumm SM, et al. Among authors: roti g. Chem Biol. 2013 May 23;20(5):713-25. doi: 10.1016/j.chembiol.2013.03.020. Chem Biol. 2013. PMID: 23706636 Free PMC article.
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia.
Baldoni S, Del Papa B, Dorillo E, Aureli P, De Falco F, Rompietti C, Sorcini D, Varasano E, Cecchini D, Zei T, Di Tommaso A, Rosati E, Alexe G, Roti G, Stegmaier K, Di Ianni M, Falzetti F, Sportoletti P. Baldoni S, et al. Among authors: roti g. Int J Cancer. 2018 Aug 15;143(4):958-970. doi: 10.1002/ijc.31355. Epub 2018 Mar 23. Int J Cancer. 2018. PMID: 29508386 Free PMC article.
63 results