Rotter CJ - Search Results

1

Optimizing PK properties of cyclic peptides: the effect of side chain substitutions on permeability and clearance().

Rand AC, Leung SS, Eng H, Rotter CJ, Sharma R, Kalgutkar AS, Zhang Y, Varma MV, Farley KA, Khunte B, Limberakis C, Price DA, Liras S, Mathiowetz AM, Jacobson MP, Lokey RS. Rand AC, et al. Among authors: rotter cj. Medchemcomm. 2012 Oct;3(10):1282-1289. doi: 10.1039/C2MD20203D. Medchemcomm. 2012. PMID: 23133740 Free PMC article.

2

Improving on nature: making a cyclic heptapeptide orally bioavailable.

Nielsen DS, Hoang HN, Lohman RJ, Hill TA, Lucke AJ, Craik DJ, Edmonds DJ, Griffith DA, Rotter CJ, Ruggeri RB, Price DA, Liras S, Fairlie DP. Nielsen DS, et al. Among authors: rotter cj. Angew Chem Int Ed Engl. 2014 Nov 3;53(45):12059-63. doi: 10.1002/anie.201405364. Epub 2014 Sep 12. Angew Chem Int Ed Engl. 2014. PMID: 25219505

3

Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed.

Hill TA, Lohman RJ, Hoang HN, Nielsen DS, Scully CC, Kok WM, Liu L, Lucke AJ, Stoermer MJ, Schroeder CI, Chaousis S, Colless B, Bernhardt PV, Edmonds DJ, Griffith DA, Rotter CJ, Ruggeri RB, Price DA, Liras S, Craik DJ, Fairlie DP. Hill TA, et al. Among authors: rotter cj. ACS Med Chem Lett. 2014 Aug 4;5(10):1148-51. doi: 10.1021/ml5002823. eCollection 2014 Oct 9. ACS Med Chem Lett. 2014. PMID: 25313329 Free PMC article.

4

The Antimicrobial Agent Fusidic Acid Inhibits Organic Anion Transporting Polypeptide-Mediated Hepatic Clearance and May Potentiate Statin-Induced Myopathy.

Eng H, Scialis RJ, Rotter CJ, Lin J, Lazzaro S, Varma MV, Di L, Feng B, West M, Kalgutkar AS. Eng H, et al. Among authors: rotter cj. Drug Metab Dispos. 2016 May;44(5):692-9. doi: 10.1124/dmd.115.067447. Epub 2016 Feb 17. Drug Metab Dispos. 2016. PMID: 26888941

5

High specificity in response of the sodium-dependent multivitamin transporter to derivatives of pantothenic acid.

Chirapu SR, Rotter CJ, Miller EL, Varma MV, Dow RL, Finn MG. Chirapu SR, et al. Among authors: rotter cj. Curr Top Med Chem. 2013;13(7):837-42. doi: 10.2174/1568026611313070006. Curr Top Med Chem. 2013. PMID: 23578027 Review.

6

Targeting intestinal transporters for optimizing oral drug absorption.

Varma MV, Ambler CM, Ullah M, Rotter CJ, Sun H, Litchfield J, Fenner KS, El-Kattan AF. Varma MV, et al. Among authors: rotter cj. Curr Drug Metab. 2010 Nov;11(9):730-42. doi: 10.2174/138920010794328850. Curr Drug Metab. 2010. PMID: 21189135 Review.

7

Elucidation of the biochemical basis for a clinical drug-drug interaction between atorvastatin and 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methyl benzoic acid (CP-778875), a subtype selective agonist of the peroxisome proliferator-activated receptor alpha.

Kalgutkar AS, Chen D, Varma MV, Feng B, Terra SG, Scialis RJ, Rotter CJ, Frederick KS, West MA, Goosen TC, Gosset JR, Walsky RL, Francone OL. Kalgutkar AS, et al. Among authors: rotter cj. Xenobiotica. 2013 Nov;43(11):963-72. doi: 10.3109/00498254.2013.791004. Epub 2013 Apr 30. Xenobiotica. 2013. PMID: 23631744

8

Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.

Varma MV, Obach RS, Rotter C, Miller HR, Chang G, Steyn SJ, El-Kattan A, Troutman MD. Varma MV, et al. J Med Chem. 2010 Feb 11;53(3):1098-108. doi: 10.1021/jm901371v. J Med Chem. 2010. PMID: 20070106

9

Quantitative assessment of the contribution of sodium-dependent taurocholate co-transporting polypeptide (NTCP) to the hepatic uptake of rosuvastatin, pitavastatin and fluvastatin.

Bi YA, Qiu X, Rotter CJ, Kimoto E, Piotrowski M, Varma MV, Ei-Kattan AF, Lai Y. Bi YA, et al. Among authors: rotter cj. Biopharm Drug Dispos. 2013 Nov;34(8):452-61. doi: 10.1002/bdd.1861. Epub 2013 Oct 3. Biopharm Drug Dispos. 2013. PMID: 23996477

10

Quantitative prediction of renal transporter-mediated clinical drug-drug interactions.

Feng B, Hurst S, Lu Y, Varma MV, Rotter CJ, El-Kattan A, Lockwood P, Corrigan B. Feng B, et al. Among authors: rotter cj. Mol Pharm. 2013 Nov 4;10(11):4207-15. doi: 10.1021/mp400295c. Epub 2013 Oct 10. Mol Pharm. 2013. PMID: 24066726

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

26 results

Search Page