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Mutant p53 gain-of-function in cancer.
Oren M, Rotter V. Oren M, et al. Among authors: rotter v. Cold Spring Harb Perspect Biol. 2010 Feb;2(2):a001107. doi: 10.1101/cshperspect.a001107. Cold Spring Harb Perspect Biol. 2010. PMID: 20182618 Free PMC article. Review.
p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation.
Brosh R, Shalgi R, Liran A, Landan G, Korotayev K, Nguyen GH, Enerly E, Johnsen H, Buganim Y, Solomon H, Goldstein I, Madar S, Goldfinger N, Børresen-Dale AL, Ginsberg D, Harris CC, Pilpel Y, Oren M, Rotter V. Brosh R, et al. Among authors: rotter v. Mol Syst Biol. 2008;4:229. doi: 10.1038/msb.2008.65. Epub 2008 Nov 25. Mol Syst Biol. 2008. PMID: 19034270 Free PMC article.
Modulation of the vitamin D3 response by cancer-associated mutant p53.
Stambolsky P, Tabach Y, Fontemaggi G, Weisz L, Maor-Aloni R, Siegfried Z, Shiff I, Kogan I, Shay M, Kalo E, Blandino G, Simon I, Oren M, Rotter V. Stambolsky P, et al. Among authors: rotter v. Cancer Cell. 2010 Mar 16;17(3):273-85. doi: 10.1016/j.ccr.2009.11.025. Cancer Cell. 2010. PMID: 20227041 Free PMC article.
Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.
Cooks T, Pateras IS, Tarcic O, Solomon H, Schetter AJ, Wilder S, Lozano G, Pikarsky E, Forshew T, Rosenfeld N, Harpaz N, Itzkowitz S, Harris CC, Rotter V, Gorgoulis VG, Oren M. Cooks T, et al. Among authors: rotter v. Cancer Cell. 2013 May 13;23(5):634-46. doi: 10.1016/j.ccr.2013.03.022. Cancer Cell. 2013. PMID: 23680148 Free PMC article.
Targeting mutant p53 for cancer therapy.
Oren M, Tal P, Rotter V. Oren M, et al. Among authors: rotter v. Aging (Albany NY). 2016 Jun;8(6):1159-60. doi: 10.18632/aging.100992. Aging (Albany NY). 2016. PMID: 27347904 Free PMC article. No abstract available.
Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers.
Solomon H, Dinowitz N, Pateras IS, Cooks T, Shetzer Y, Molchadsky A, Charni M, Rabani S, Koifman G, Tarcic O, Porat Z, Kogan-Sakin I, Goldfinger N, Oren M, Harris CC, Gorgoulis VG, Rotter V. Solomon H, et al. Among authors: rotter v. Oncogene. 2018 Mar;37(12):1669-1684. doi: 10.1038/s41388-017-0060-8. Epub 2018 Jan 18. Oncogene. 2018. PMID: 29343849 Free PMC article.
305 results