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LC3/GABARAP family proteins: autophagy-(un)related functions.
Schaaf MB, Keulers TG, Vooijs MA, Rouschop KM. Schaaf MB, et al. Among authors: rouschop km. FASEB J. 2016 Dec;30(12):3961-3978. doi: 10.1096/fj.201600698R. Epub 2016 Sep 6. FASEB J. 2016. PMID: 27601442 Review.
EGFRvIII expression triggers a metabolic dependency and therapeutic vulnerability sensitive to autophagy inhibition.
Jutten B, Keulers TG, Peeters HJM, Schaaf MBE, Savelkouls KGM, Compter I, Clarijs R, Schijns OEMG, Ackermans L, Teernstra OPM, Zonneveld MI, Colaris RME, Dubois L, Vooijs MA, Bussink J, Sotelo J, Theys J, Lammering G, Rouschop KMA. Jutten B, et al. Autophagy. 2018;14(2):283-295. doi: 10.1080/15548627.2017.1409926. Epub 2018 Jan 29. Autophagy. 2018. PMID: 29377763 Free PMC article.
GABARAPL1 is required for increased EGFR membrane expression during hypoxia.
Keulers TG, Schaaf MB, Peeters HJ, Savelkouls KG, Vooijs MA, Bussink J, Jutten B, Rouschop KM. Keulers TG, et al. Among authors: rouschop km. Radiother Oncol. 2015 Sep;116(3):417-22. doi: 10.1016/j.radonc.2015.06.023. Epub 2015 Jul 8. Radiother Oncol. 2015. PMID: 26164772
Canonical autophagy does not contribute to cellular radioresistance.
Schaaf MB, Jutten B, Keulers TG, Savelkouls KG, Peeters HJ, van den Beucken T, van Schooten FJ, Godschalk RW, Vooijs M, Rouschop KM. Schaaf MB, et al. Among authors: rouschop km. Radiother Oncol. 2015 Mar;114(3):406-12. doi: 10.1016/j.radonc.2015.02.019. Epub 2015 Mar 13. Radiother Oncol. 2015. PMID: 25779723
64 results