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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1995 1
1999 1
2000 4
2001 1
2005 1
2007 1
2008 1
2009 1
2010 2
2011 1
2012 3
2014 2
2016 1
2017 5
2018 8
2019 11
2020 1
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Ipatasertib plus paclitaxel versus placebo plus paclitaxel as first-line therapy for metastatic triple-negative breast cancer (LOTUS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
Kim SB, et al. Lancet Oncol 2017 - Clinical Trial. PMID 28800861 Free PMC article.
Median progression-free survival in the intention-to-treat population was 6·2 months (95% CI 3·8-9·0) with ipatasertib versus 4·9 months (3·6-5·4) with placebo (stratified hazard ratio [HR] 0·60, 95% CI 0·37-0·98; p=0·037) and in the 48 patients with PTEN-low tumours, median progression-free survival was 6·2 months (95% CI 3·6-9·1) with ipatasertib versus 3·7 months (1·9-7·3) with placebo (stratified HR 0·59, 95% CI 0·26-1·32, p=0·18). ...
Median progression-free survival in the intention-to-treat population was 6·2 months (95% CI 3·8-9·0) with ipatasertib versus 4·9 months (3· …
Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality
Soler Artigas M, et al. Mol Psychiatry 2019. Among authors: Rovira P. PMID 30610198
We estimated their genetic correlation to be r(2) = 0.29 (P = 1.63 × 10(-5)) and identified four new genome-wide significant loci in a cross-trait analysis: two in a single variant association analysis (rs145108385, P = 3.30 × 10(-8) and rs4259397, P = 4.52 × 10(-8)) and two in a gene-based association analysis (WDPCP, P = 9.67 × 10(-7) and ZNF251, P = 1.62 × 10(-6)). Using a two-sample Mendelian randomization approach we found support that ADHD is causal for lifetime cannabis use, with an odds ratio of 7.9 for cannabis use in individuals with ADHD in comparison to individuals without ADHD (95% CI (3.72, 15.51), P = 5.88 × 10(-5)). ...
We estimated their genetic correlation to be r(2) = 0.29 (P = 1.63 × 10(-5)) and identified four new genome-wide significant loci in …
Integrative genomic analysis of methylphenidate response in attention-deficit/hyperactivity disorder
Pagerols M, et al. Sci Rep 2018. Among authors: Rovira P. PMID 29382897 Free PMC article.
Although no variant reached genome-wide significance, the set of genes containing single-nucleotide polymorphisms (SNPs) nominally associated with MPH response (P < 0.05) was significantly enriched for candidates previously studied in ADHD or treatment outcome. ...
Although no variant reached genome-wide significance, the set of genes containing single-nucleotide polymorphisms (SNPs) nominally associate …
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