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Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance.
Pang KS, Rowland M. Pang KS, et al. Among authors: rowland m. J Pharmacokinet Biopharm. 1977 Dec;5(6):625-53. doi: 10.1007/BF01059688. J Pharmacokinet Biopharm. 1977. PMID: 599411 No abstract available.
Models of hepatic elimination: comparison of stochastic models to describe residence time distributions and to predict the influence of drug distribution, enzyme heterogeneity, and systemic recycling on hepatic elimination.
Roberts MS, Donaldson JD, Rowland M. Roberts MS, et al. Among authors: rowland m. J Pharmacokinet Biopharm. 1988 Feb;16(1):41-83. doi: 10.1007/BF01061862. J Pharmacokinet Biopharm. 1988. PMID: 3373419
Protein binding and hepatic clearance: discrimination between models of hepatic clearance with diazepam, a drug of high intrinsic clearance, in the isolated perfused rat liver preparation.
Rowland M, Leitch D, Fleming G, Smith B. Rowland M, et al. J Pharmacokinet Biopharm. 1984 Apr;12(2):129-47. doi: 10.1007/BF01059274. J Pharmacokinet Biopharm. 1984. PMID: 6491897
Models of hepatic drug clearance: discrimination between the 'well stirred' and 'parallel-tube' models.
Ahmad AB, Bennett PN, Rowland M. Ahmad AB, et al. Among authors: rowland m. J Pharm Pharmacol. 1983 Apr;35(4):219-24. doi: 10.1111/j.2042-7158.1983.tb02916.x. J Pharm Pharmacol. 1983. PMID: 6133930
Clearance concepts in pharmacokinetics.
Rowland M, Benet LZ, Graham GG. Rowland M, et al. J Pharmacokinet Biopharm. 1973 Apr;1(2):123-36. doi: 10.1007/BF01059626. J Pharmacokinet Biopharm. 1973. PMID: 4764426 No abstract available.
Plasma protein binding and therapeutic drug monitoring.
Rowland M. Rowland M. Ther Drug Monit. 1980;2(1):29-37. doi: 10.1097/00007691-198001000-00005. Ther Drug Monit. 1980. PMID: 6762701 Review. No abstract available.
In vivo evaluation of Michaelis-Menten constants of hepatic drug-eliminating systems.
Pang KS, Rowland M, Tozer TN. Pang KS, et al. Among authors: rowland m. Drug Metab Dispos. 1978 Mar-Apr;6(2):197-200. Drug Metab Dispos. 1978. PMID: 26537 No abstract available.
Drug interactions.
Rowland M. Rowland M. Adv Biol Skin. 1972;12:235-55. Adv Biol Skin. 1972. PMID: 4579195 Review. No abstract available.
Application of the dispersion model to describe disposition kinetics of markers in the dual perfused rat liver.
Sahin S, Rowland M. Sahin S, et al. Among authors: rowland m. Drug Metab Dispos. 2007 Jul;35(7):1119-25. doi: 10.1124/dmd.106.013813. Epub 2007 Apr 12. Drug Metab Dispos. 2007. PMID: 17431032
Measurement of binding of basic drugs to acidic phospholipids using surface plasmon resonance and incorporation of the data into mechanistic tissue composition equations to predict steady-state volume of distribution.
Small H, Gardner I, Jones HM, Davis J, Rowland M. Small H, et al. Among authors: rowland m. Drug Metab Dispos. 2011 Oct;39(10):1789-93. doi: 10.1124/dmd.111.040253. Epub 2011 Jul 15. Drug Metab Dispos. 2011. PMID: 21764943
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