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1,931 results
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Cracking the phosphatase code: docking interactions determine substrate specificity.
Roy J, Cyert MS. Roy J, et al. Sci Signal. 2009 Dec 8;2(100):re9. doi: 10.1126/scisignal.2100re9. Sci Signal. 2009. PMID: 19996458 Review.
A conserved docking site modulates substrate affinity for calcineurin, signaling output, and in vivo function.
Roy J, Li H, Hogan PG, Cyert MS. Roy J, et al. Mol Cell. 2007 Mar 23;25(6):889-901. doi: 10.1016/j.molcel.2007.02.014. Mol Cell. 2007. PMID: 17386265 Free PMC article.
A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants.
Rodríguez A, Roy J, Martínez-Martínez S, López-Maderuelo MD, Niño-Moreno P, Ortí L, Pantoja-Uceda D, Pineda-Lucena A, Cyert MS, Redondo JM. Rodríguez A, et al. Among authors: roy j. Mol Cell. 2009 Mar 13;33(5):616-26. doi: 10.1016/j.molcel.2009.01.030. Mol Cell. 2009. PMID: 19285944 Free PMC article.
The calcineurin signaling network evolves via conserved kinase-phosphatase modules that transcend substrate identity.
Goldman A, Roy J, Bodenmiller B, Wanka S, Landry CR, Aebersold R, Cyert MS. Goldman A, et al. Among authors: roy j. Mol Cell. 2014 Aug 7;55(3):422-435. doi: 10.1016/j.molcel.2014.05.012. Epub 2014 Jun 12. Mol Cell. 2014. PMID: 24930733 Free PMC article.
Hcm1 integrates signals from Cdk1 and calcineurin to control cell proliferation.
Arsenault HE, Roy J, Mapa CE, Cyert MS, Benanti JA. Arsenault HE, et al. Among authors: roy j. Mol Biol Cell. 2015 Oct 15;26(20):3570-7. doi: 10.1091/mbc.E15-07-0469. Epub 2015 Aug 12. Mol Biol Cell. 2015. PMID: 26269584 Free PMC article.
Identifying New Substrates and Functions for an Old Enzyme: Calcineurin.
Roy J, Cyert MS. Roy J, et al. Cold Spring Harb Perspect Biol. 2020 Mar 2;12(3):a035436. doi: 10.1101/cshperspect.a035436. Cold Spring Harb Perspect Biol. 2020. PMID: 31308145 Review.
A calcineurin-Hoxb13 axis regulates growth mode of mammalian cardiomyocytes.
Nguyen NUN, Canseco DC, Xiao F, Nakada Y, Li S, Lam NT, Muralidhar SA, Savla JJ, Hill JA, Le V, Zidan KA, El-Feky HW, Wang Z, Ahmed MS, Hubbi ME, Menendez-Montes I, Moon J, Ali SR, Le V, Villalobos E, Mohamed MS, Elhelaly WM, Thet S, Anene-Nzelu CG, Tan WLW, Foo RS, Meng X, Kanchwala M, Xing C, Roy J, Cyert MS, Rothermel BA, Sadek HA. Nguyen NUN, et al. Among authors: roy j. Nature. 2020 Jun;582(7811):271-276. doi: 10.1038/s41586-020-2228-6. Epub 2020 Apr 22. Nature. 2020. PMID: 32499640 Free PMC article.
Cell Biology: Deciphering the ABCs of SLiMs in G1-CDK Signaling.
Roy J, Cyert MS. Roy J, et al. Curr Biol. 2020 Nov 16;30(22):R1382-R1385. doi: 10.1016/j.cub.2020.09.026. Curr Biol. 2020. PMID: 33202241
Quantitative mapping of protein-peptide affinity landscapes using spectrally encoded beads.
Nguyen HQ, Roy J, Harink B, Damle NP, Latorraca NR, Baxter BC, Brower K, Longwell SA, Kortemme T, Thorn KS, Cyert MS, Fordyce PM. Nguyen HQ, et al. Among authors: roy j. Elife. 2019 Jul 8;8:e40499. doi: 10.7554/eLife.40499. Elife. 2019. PMID: 31282865 Free PMC article.
A novel pseudoknot element is essential for the action of a yeast telomerase.
Tzfati Y, Knight Z, Roy J, Blackburn EH. Tzfati Y, et al. Among authors: roy j. Genes Dev. 2003 Jul 15;17(14):1779-88. doi: 10.1101/gad.1099403. Epub 2003 Jun 27. Genes Dev. 2003. PMID: 12832393 Free PMC article.
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