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IGF-I: an essential factor in terminal end bud formation and ductal morphogenesis.
Kleinberg DL, Feldman M, Ruan W. Kleinberg DL, et al. Among authors: ruan w. J Mammary Gland Biol Neoplasia. 2000 Jan;5(1):7-17. doi: 10.1023/a:1009507030633. J Mammary Gland Biol Neoplasia. 2000. PMID: 10791764 Review.
Lipid metabolism in phosphatidylinositol transfer protein alpha-deficient vibrator mice.
Monaco ME, Kim J, Ruan W, Wieczorek R, Kleinberg DL, Walden PD. Monaco ME, et al. Among authors: ruan w. Biochem Biophys Res Commun. 2004 Apr 30;317(2):444-50. doi: 10.1016/j.bbrc.2004.03.054. Biochem Biophys Res Commun. 2004. PMID: 15063778
IGF-I, GH, and sex steroid effects in normal mammary gland development.
Kleinberg DL, Ruan W. Kleinberg DL, et al. Among authors: ruan w. J Mammary Gland Biol Neoplasia. 2008 Dec;13(4):353-60. doi: 10.1007/s10911-008-9103-7. Epub 2008 Nov 25. J Mammary Gland Biol Neoplasia. 2008. PMID: 19034633
Insulin-like growth factor (IGF)-I controls prostate fibromuscular development: IGF-I inhibition prevents both fibromuscular and glandular development in eugonadal mice.
Kleinberg DL, Ruan W, Yee D, Kovacs KT, Vidal S. Kleinberg DL, et al. Among authors: ruan w. Endocrinology. 2007 Mar;148(3):1080-8. doi: 10.1210/en.2006-1272. Epub 2006 Nov 30. Endocrinology. 2007. PMID: 17138659
Progesterone stimulates mammary gland ductal morphogenesis by synergizing with and enhancing insulin-like growth factor-I action.
Ruan W, Monaco ME, Kleinberg DL. Ruan W, et al. Endocrinology. 2005 Mar;146(3):1170-8. doi: 10.1210/en.2004-1360. Epub 2004 Dec 16. Endocrinology. 2005. PMID: 15604210
SOM230 inhibits insulin-like growth factor-I action in mammary gland development by pituitary independent mechanism: mediated through somatostatin subtype receptor 3?
Ruan W, Fahlbusch F, Clemmons DR, Monaco ME, Walden PD, Silva AP, Schmid HA, Kleinberg DL. Ruan W, et al. Mol Endocrinol. 2006 Feb;20(2):426-36. doi: 10.1210/me.2005-0283. Epub 2005 Oct 13. Mol Endocrinol. 2006. PMID: 16223973
The effect of GH on estrogen receptor expression in the rat mammary gland.
Feldman M, Ruan W, Tappin I, Wieczorek R, Kleinberg DL. Feldman M, et al. Among authors: ruan w. J Endocrinol. 1999 Dec;163(3):515-22. doi: 10.1677/joe.0.1630515. J Endocrinol. 1999. PMID: 10588825
Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development.
Ruan W, Kleinberg DL. Ruan W, et al. Endocrinology. 1999 Nov;140(11):5075-81. doi: 10.1210/endo.140.11.7095. Endocrinology. 1999. PMID: 10537134
Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development.
Ruan W, Powell-Braxton L, Kopchick JJ, Kleinberg DL. Ruan W, et al. Endocrinology. 1999 May;140(5):1984-9. doi: 10.1210/endo.140.5.6721. Endocrinology. 1999. PMID: 10218945
Evidence that the mammary fat pad mediates the action of growth hormone in mammary gland development.
Walden PD, Ruan W, Feldman M, Kleinberg DL. Walden PD, et al. Among authors: ruan w. Endocrinology. 1998 Feb;139(2):659-62. doi: 10.1210/endo.139.2.5718. Endocrinology. 1998. PMID: 9449638
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