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IL-1 family nomenclature.
Dinarello C, Arend W, Sims J, Smith D, Blumberg H, O'Neill L, Goldbach-Mansky R, Pizarro T, Hoffman H, Bufler P, Nold M, Ghezzi P, Mantovani A, Garlanda C, Boraschi D, Rubartelli A, Netea M, van der Meer J, Joosten L, Mandrup-Poulsen T, Donath M, Lewis E, Pfeilschifter J, Martin M, Kracht M, Muehl H, Novick D, Lukic M, Conti B, Solinger A, Kelk P, van de Veerdonk F, Gabel C. Dinarello C, et al. Among authors: rubartelli a. Nat Immunol. 2010 Nov;11(11):973. doi: 10.1038/ni1110-973. Nat Immunol. 2010. PMID: 20959797 Free PMC article. No abstract available.
Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages.
Netea MG, Nold-Petry CA, Nold MF, Joosten LA, Opitz B, van der Meer JH, van de Veerdonk FL, Ferwerda G, Heinhuis B, Devesa I, Funk CJ, Mason RJ, Kullberg BJ, Rubartelli A, van der Meer JW, Dinarello CA. Netea MG, et al. Among authors: rubartelli a. Blood. 2009 Mar 5;113(10):2324-35. doi: 10.1182/blood-2008-03-146720. Epub 2008 Dec 22. Blood. 2009. PMID: 19104081 Free PMC article.
OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, Scribner CL, Barrow RB, Altman RD, Skouras DB, Gattorno M, Grau V, Janciauskiene S, Rubartelli A, Joosten LAB, Dinarello CA. Marchetti C, et al. Among authors: rubartelli a. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1530-E1539. doi: 10.1073/pnas.1716095115. Epub 2018 Jan 29. Proc Natl Acad Sci U S A. 2018. PMID: 29378952 Free PMC article.
The secretion of IL-1β and options for release.
Piccioli P, Rubartelli A. Piccioli P, et al. Among authors: rubartelli a. Semin Immunol. 2013 Dec 15;25(6):425-9. doi: 10.1016/j.smim.2013.10.007. Epub 2013 Nov 5. Semin Immunol. 2013. PMID: 24201029 Review.
142 results