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Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16.
Shi CH, Rubel C, Soss SE, Sanchez-Hodge R, Zhang S, Madrigal SC, Ravi S, McDonough H, Page RC, Chazin WJ, Patterson C, Mao CY, Willis MS, Luo HY, Li YS, Stevens DA, Tang MB, Du P, Wang YH, Hu ZW, Xu YM, Schisler JC. Shi CH, et al. PLoS Genet. 2018 Sep 17;14(9):e1007664. doi: 10.1371/journal.pgen.1007664. eCollection 2018 Sep. PLoS Genet. 2018. PMID: 30222779 Free PMC article.
CHIP Regulates Aquaporin-2 Quality Control and Body Water Homeostasis.
Wu Q, Moeller HB, Stevens DA, Sanchez-Hodge R, Childers G, Kortenoeven MLA, Cheng L, Rosenbaek LL, Rubel C, Patterson C, Pisitkun T, Schisler JC, Fenton RA. Wu Q, et al. J Am Soc Nephrol. 2018 Mar;29(3):936-948. doi: 10.1681/ASN.2017050526. Epub 2017 Dec 14. J Am Soc Nephrol. 2018. PMID: 29242247 Free PMC article.
Independent study demonstrates amyloid probability score accurately indicates amyloid pathology.
Fogelman I, West T, Braunstein JB, Verghese PB, Kirmess KM, Meyer MR, Contois JH, Shobin E, Ferber KL, Gagnon J, Rubel CE, Graham D, Bateman RJ, Holtzman DM, Huang S, Yu J, Yang S, Yarasheski KE. Fogelman I, et al. Among authors: rubel ce. Ann Clin Transl Neurol. 2023 May;10(5):765-778. doi: 10.1002/acn3.51763. Epub 2023 Mar 28. Ann Clin Transl Neurol. 2023. PMID: 36975407 Free PMC article.
Comparative analytical performance of multiple plasma Aβ42 and Aβ40 assays and their ability to predict positron emission tomography amyloid positivity.
Zicha S, Bateman RJ, Shaw LM, Zetterberg H, Bannon AW, Horton WA, Baratta M, Kolb HC, Dobler I, Mordashova Y, Saad ZS, Raunig DL, Spanakis EM, Li Y, Schindler SE, Ferber K, Rubel CE, Martone RL, Weber CJ, Edelmayer RM, Meyers EA, Bollinger JG, Rosenbaugh EG, Potter WZ; Alzheimer's Disease Neuroimaging Initiative (ADNI); Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium Plasma Aβ as a Predictor of Amyloid Positivity in Alzheimer's Disease Project Team. Zicha S, et al. Among authors: rubel ce. Alzheimers Dement. 2022 Jul 12:10.1002/alz.12697. doi: 10.1002/alz.12697. Online ahead of print. Alzheimers Dement. 2022. PMID: 35820077 Free PMC article.