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Safety issues and prospects for future generations of PPAR modulators.
Rubenstrunk A, Hanf R, Hum DW, Fruchart JC, Staels B. Rubenstrunk A, et al. Biochim Biophys Acta. 2007 Aug;1771(8):1065-81. doi: 10.1016/j.bbalip.2007.02.003. Epub 2007 Feb 24. Biochim Biophys Acta. 2007. PMID: 17428730 Review.
Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.
Staels B, Rubenstrunk A, Noel B, Rigou G, Delataille P, Millatt LJ, Baron M, Lucas A, Tailleux A, Hum DW, Ratziu V, Cariou B, Hanf R. Staels B, et al. Among authors: rubenstrunk a. Hepatology. 2013 Dec;58(6):1941-52. doi: 10.1002/hep.26461. Epub 2013 Oct 29. Hepatology. 2013. PMID: 23703580 Clinical Trial.
Positive in vivo heterologous gene regulation by electric pulses delivery with metallothionein I gene promoter.
Rubenstrunk A, Trollet C, Orsini C, Scherman D. Rubenstrunk A, et al. J Gene Med. 2005 Dec;7(12):1565-72. doi: 10.1002/jgm.811. J Gene Med. 2005. PMID: 16142828
Delivery of electric pulses for DNA electrotransfer to mouse muscle does not induce the expression of stress related genes.
Rubenstrunk A, Mahfoudi A, Scherman D. Rubenstrunk A, et al. Cell Biol Toxicol. 2004 Feb;20(1):25-31. doi: 10.1023/b:cbto.0000021079.69089.4f. Cell Biol Toxicol. 2004. PMID: 15119845
Transcriptional activation of the metallothionein I gene by electric pulses in vivo: basis for the development of a new gene switch system.
Rubenstrunk A, Orsini C, Mahfoudi A, Scherman D. Rubenstrunk A, et al. J Gene Med. 2003 Sep;5(9):773-83. doi: 10.1002/jgm.360. J Gene Med. 2003. PMID: 12950068
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