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A comparison of non-integrating reprogramming methods.
Schlaeger TM, Daheron L, Brickler TR, Entwisle S, Chan K, Cianci A, DeVine A, Ettenger A, Fitzgerald K, Godfrey M, Gupta D, McPherson J, Malwadkar P, Gupta M, Bell B, Doi A, Jung N, Li X, Lynes MS, Brookes E, Cherry AB, Demirbas D, Tsankov AM, Zon LI, Rubin LL, Feinberg AP, Meissner A, Cowan CA, Daley GQ. Schlaeger TM, et al. Among authors: rubin ll. Nat Biotechnol. 2015 Jan;33(1):58-63. doi: 10.1038/nbt.3070. Epub 2014 Dec 1. Nat Biotechnol. 2015. PMID: 25437882 Free PMC article.
A TALEN genome-editing system for generating human stem cell-based disease models.
Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, Schinzel RT, Xia F, Tang A, Xia Y, Figueroa E, Wann A, Ahfeldt T, Daheron L, Zhang F, Rubin LL, Peng LF, Chung RT, Musunuru K, Cowan CA. Ding Q, et al. Among authors: rubin ll. Cell Stem Cell. 2013 Feb 7;12(2):238-51. doi: 10.1016/j.stem.2012.11.011. Epub 2012 Dec 13. Cell Stem Cell. 2013. PMID: 23246482 Free PMC article.
A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS.
Yang YM, Gupta SK, Kim KJ, Powers BE, Cerqueira A, Wainger BJ, Ngo HD, Rosowski KA, Schein PA, Ackeifi CA, Arvanites AC, Davidow LS, Woolf CJ, Rubin LL. Yang YM, et al. Among authors: rubin ll. Cell Stem Cell. 2013 Jun 6;12(6):713-26. doi: 10.1016/j.stem.2013.04.003. Epub 2013 Apr 18. Cell Stem Cell. 2013. PMID: 23602540 Free PMC article.
Notch inhibition allows oncogene-independent generation of iPS cells.
Ichida JK, Tcw J, Williams LA, Carter AC, Shi Y, Moura MT, Ziller M, Singh S, Amabile G, Bock C, Umezawa A, Rubin LL, Bradner JE, Akutsu H, Meissner A, Eggan K. Ichida JK, et al. Among authors: rubin ll. Nat Chem Biol. 2014 Aug;10(8):632-639. doi: 10.1038/nchembio.1552. Epub 2014 Jun 22. Nat Chem Biol. 2014. PMID: 24952596 Free PMC article.
Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes.
Xue R, Lynes MD, Dreyfuss JM, Shamsi F, Schulz TJ, Zhang H, Huang TL, Townsend KL, Li Y, Takahashi H, Weiner LS, White AP, Lynes MS, Rubin LL, Goodyear LJ, Cypess AM, Tseng YH. Xue R, et al. Among authors: rubin ll. Nat Med. 2015 Jul;21(7):760-8. doi: 10.1038/nm.3881. Epub 2015 Jun 15. Nat Med. 2015. PMID: 26076036 Free PMC article.
Applying Deep Neural Network Analysis to High-Content Image-Based Assays.
Yang SJ, Lipnick SL, Makhortova NR, Venugopalan S, Fan M, Armstrong Z, Schlaeger TM, Deng L, Chung WK, O'Callaghan L, Geraschenko A, Whye D, Berndl M, Hazard J, Williams B, Narayanaswamy A, Ando DM, Nelson P, Rubin LL. Yang SJ, et al. Among authors: rubin ll. SLAS Discov. 2019 Sep;24(8):829-841. doi: 10.1177/2472555219857715. Epub 2019 Jul 8. SLAS Discov. 2019. PMID: 31284814 Free PMC article.
Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis.
Toyohara T, Roudnicky F, Florido MHC, Nakano T, Yu H, Katsuki S, Lee M, Meissner T, Friesen M, Davidow LS, Ptaszek L, Abe T, Rubin LL, Pereira AC, Aikawa M, Cowan CA. Toyohara T, et al. Among authors: rubin ll. Cell Stem Cell. 2020 Jul 2;27(1):147-157.e7. doi: 10.1016/j.stem.2020.04.018. Epub 2020 May 14. Cell Stem Cell. 2020. PMID: 32413331 Free PMC article.
157 results