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Risks and benefits of phase 1 oncology trials, 1991 through 2002.
Horstmann E, McCabe MS, Grochow L, Yamamoto S, Rubinstein L, Budd T, Shoemaker D, Emanuel EJ, Grady C. Horstmann E, et al. Among authors: rubinstein l. N Engl J Med. 2005 Mar 3;352(9):895-904. doi: 10.1056/NEJMsa042220. N Engl J Med. 2005. PMID: 15745980 Free article.
Clinical toxicity associated with tiazofurin.
Grem JL, Rubinstein L, King SA, Cheson BD, Hawkins MJ, Shoemaker DD. Grem JL, et al. Among authors: rubinstein l. Invest New Drugs. 1990 May;8(2):227-38. doi: 10.1007/BF00177266. Invest New Drugs. 1990. PMID: 2200759 Review.
The statistics of phase 0 trials.
Rubinstein LV, Steinberg SM, Kummar S, Kinders R, Parchment RE, Murgo AJ, Tomaszewski JE, Doroshow JH. Rubinstein LV, et al. Stat Med. 2010 May 10;29(10):1072-6. doi: 10.1002/sim.3840. Stat Med. 2010. PMID: 20419759 Free PMC article.
Trends in Grade 5 Toxicity and Response in Phase I Trials in Hematologic Malignancy: 20-Year Experience From the Cancer Therapy Evaluation Program at the National Cancer Institute.
Chihara D, Huang EP, Finnigan SR, Cordes LM, Skorupan N, Fukuda Y, Rubinstein LV, Ivy SP, Doroshow JH, Nastoupil LJ, Flowers CR, Takebe N. Chihara D, et al. J Clin Oncol. 2022 Jun 10;40(17):1949-1957. doi: 10.1200/JCO.21.02190. Epub 2022 Mar 9. J Clin Oncol. 2022. PMID: 35263120 Free PMC article. Clinical Trial.
432 results