Rubinsztein DC - Search Results

1

A block of autophagy in lysosomal storage disorders.

Settembre C, Fraldi A, Jahreiss L, Spampanato C, Venturi C, Medina D, de Pablo R, Tacchetti C, Rubinsztein DC, Ballabio A. Settembre C, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2008 Jan 1;17(1):119-29. doi: 10.1093/hmg/ddm289. Epub 2007 Oct 3. Hum Mol Genet. 2008. PMID: 17913701

2

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy.

Ravikumar B, Duden R, Rubinsztein DC. Ravikumar B, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2002 May 1;11(9):1107-17. doi: 10.1093/hmg/11.9.1107. Hum Mol Genet. 2002. PMID: 11978769

3

Raised intracellular glucose concentrations reduce aggregation and cell death caused by mutant huntingtin exon 1 by decreasing mTOR phosphorylation and inducing autophagy.

Ravikumar B, Stewart A, Kita H, Kato K, Duden R, Rubinsztein DC. Ravikumar B, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2003 May 1;12(9):985-94. doi: 10.1093/hmg/ddg109. Hum Mol Genet. 2003. PMID: 12700167

4

Lithium rescues toxicity of aggregate-prone proteins in Drosophila by perturbing Wnt pathway.

Berger Z, Ttofi EK, Michel CH, Pasco MY, Tenant S, Rubinsztein DC, O'Kane CJ. Berger Z, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2005 Oct 15;14(20):3003-11. doi: 10.1093/hmg/ddi331. Epub 2005 Sep 2. Hum Mol Genet. 2005. PMID: 16141285

5

Rapamycin alleviates toxicity of different aggregate-prone proteins.

Berger Z, Ravikumar B, Menzies FM, Oroz LG, Underwood BR, Pangalos MN, Schmitt I, Wullner U, Evert BO, O'Kane CJ, Rubinsztein DC. Berger Z, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2006 Feb 1;15(3):433-42. doi: 10.1093/hmg/ddi458. Epub 2005 Dec 20. Hum Mol Genet. 2006. PMID: 16368705

6

Deleterious and protective properties of an aggregate-prone protein with a polyalanine expansion.

Berger Z, Davies JE, Luo S, Pasco MY, Majoul I, O'Kane CJ, Rubinsztein DC. Berger Z, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2006 Feb 1;15(3):453-65. doi: 10.1093/hmg/ddi460. Epub 2005 Dec 21. Hum Mol Genet. 2006. PMID: 16371423

7

Rapamycin pre-treatment protects against apoptosis.

Ravikumar B, Berger Z, Vacher C, O'Kane CJ, Rubinsztein DC. Ravikumar B, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2006 Apr 1;15(7):1209-16. doi: 10.1093/hmg/ddl036. Epub 2006 Feb 23. Hum Mol Genet. 2006. PMID: 16497721

8

Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications.

Williams A, Jahreiss L, Sarkar S, Saiki S, Menzies FM, Ravikumar B, Rubinsztein DC. Williams A, et al. Among authors: rubinsztein dc. Curr Top Dev Biol. 2006;76:89-101. doi: 10.1016/S0070-2153(06)76003-3. Curr Top Dev Biol. 2006. PMID: 17118264 Review.

9

A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.

Sarkar S, Krishna G, Imarisio S, Saiki S, O'Kane CJ, Rubinsztein DC. Sarkar S, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2008 Jan 15;17(2):170-8. doi: 10.1093/hmg/ddm294. Epub 2007 Oct 6. Hum Mol Genet. 2008. PMID: 17921520

10

Lysosomal storage diseases as disorders of autophagy.

Settembre C, Fraldi A, Rubinsztein DC, Ballabio A. Settembre C, et al. Among authors: rubinsztein dc. Autophagy. 2008 Jan;4(1):113-4. doi: 10.4161/auto.5227. Epub 2007 Oct 30. Autophagy. 2008. PMID: 18000397

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