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Adaptors and molecular scaffolds in immune cell signaling.
Rudd CE. Rudd CE. Cell. 1999 Jan 8;96(1):5-8. doi: 10.1016/s0092-8674(00)80953-8. Cell. 1999. PMID: 9989491 Review. No abstract available.
CD5 acts as a tyrosine kinase substrate within a receptor complex comprising T-cell receptor zeta chain/CD3 and protein-tyrosine kinases p56lck and p59fyn.
Burgess KE, Yamamoto M, Prasad KV, Rudd CE. Burgess KE, et al. Among authors: rudd ce. Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9311-5. doi: 10.1073/pnas.89.19.9311. Proc Natl Acad Sci U S A. 1992. PMID: 1384049 Free PMC article.
Ganglioside-induced CD4 endocytosis occurs independent of serine phosphorylation and is accompanied by dissociation of P56lck.
Repke H, Barber E, Ulbricht S, Buchner K, Hucho F, Kopp R, Scholz H, Rudd CE, Haseltine WA. Repke H, et al. Among authors: rudd ce. J Immunol. 1992 Oct 15;149(8):2585-91. J Immunol. 1992. PMID: 1401895
A Raf-1-related p110 polypeptide associates with the CD4-p56lck complex in T cells.
Prasad KV, Rudd CE. Prasad KV, et al. Among authors: rudd ce. Mol Cell Biol. 1992 Nov;12(11):5260-7. doi: 10.1128/mcb.12.11.5260. Mol Cell Biol. 1992. PMID: 1406695 Free PMC article.
Engagement of the TcR/CD3 complex stimulates p59fyn(T) activity: detection of associated proteins at 72 and 120-130 kD.
da Silva AJ, Yamamoto M, Zalvan CH, Rudd CE. da Silva AJ, et al. Among authors: rudd ce. Mol Immunol. 1992 Dec;29(12):1417-25. doi: 10.1016/0161-5890(92)90215-j. Mol Immunol. 1992. PMID: 1454062
Biochemical identification of a direct physical interaction between the CD4:p56lck and Ti(TcR)/CD3 complexes.
Burgess KE, Odysseos AD, Zalvan C, Druker BJ, Anderson P, Schlossman SF, Rudd CE. Burgess KE, et al. Among authors: rudd ce. Eur J Immunol. 1991 Jul;21(7):1663-8. doi: 10.1002/eji.1830210712. Eur J Immunol. 1991. PMID: 1829412
Molecular analysis of the interaction of p56lck with the CD4 and CD8 antigens.
Rudd CE, Barber EK, Burgess KE, Hahn JY, Odysseos AD, Sy MS, Schlossman SF. Rudd CE, et al. Adv Exp Med Biol. 1991;292:85-96. doi: 10.1007/978-1-4684-5943-2_10. Adv Exp Med Biol. 1991. PMID: 1835265
A 32-kD GTP-binding protein associated with the CD4-p56lck and CD8-p56lck T cell receptor complexes.
Telfer JC, Rudd CE. Telfer JC, et al. Among authors: rudd ce. Science. 1991 Oct 18;254(5030):439-41. doi: 10.1126/science.1925604. Science. 1991. PMID: 1925604
CD4, CD8 and the TCR-CD3 complex: a novel class of protein-tyrosine kinase receptor.
Rudd CE. Rudd CE. Immunol Today. 1990 Nov;11(11):400-6. doi: 10.1016/0167-5699(90)90159-7. Immunol Today. 1990. PMID: 1964053 Review.
Here, Christopher Rudd examines these interactions and outlines their potential roles in normal and malignant T-cell growth....
Here, Christopher Rudd examines these interactions and outlines their potential roles in normal and malignant T-cell growth....
The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.
Rudd CE, Trevillyan JM, Dasgupta JD, Wong LL, Schlossman SF. Rudd CE, et al. Proc Natl Acad Sci U S A. 1988 Jul;85(14):5190-4. doi: 10.1073/pnas.85.14.5190. Proc Natl Acad Sci U S A. 1988. PMID: 2455897 Free PMC article.
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