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Infant B cell memory differentiation and early gut bacterial colonization.
Lundell AC, Björnsson V, Ljung A, Ceder M, Johansen S, Lindhagen G, Törnhage CJ, Adlerberth I, Wold AE, Rudin A. Lundell AC, et al. J Immunol. 2012 May 1;188(9):4315-22. doi: 10.4049/jimmunol.1103223. Epub 2012 Apr 4. J Immunol. 2012. PMID: 22490441 Clinical Trial.
In a prospective newborn/infant cohort including 65 Swedish children, we examined the numbers and proportions of CD20(+), CD5(+), and CD27(+) B cells in blood samples obtained at several time points during the first 3 y of life using flow cytometry. ...
In a prospective newborn/infant cohort including 65 Swedish children, we examined the numbers and proportions of CD20(+), CD5(+), and …
Epitope specificity of a monoclonal antibody generated against the dissociated CFA/I fimbriae of enterotoxigenic Escherichia coli.
de Luna MG, Rudin A, Vinhas SA, de Almeida DF, de Souza Ferreira LC. de Luna MG, et al. Microbiol Immunol. 1998;42(5):341-6. doi: 10.1111/j.1348-0421.1998.tb02293.x. Microbiol Immunol. 1998. PMID: 9654365
A monoclonal antibody (MAb 84) raised against the dissociated CFA/I fimbriae of enterotoxigenic Escherichia coli was characterized with regard to antigen binding and epitope specificity. Enzyme-linked immunosorbent assay (ELISA) showed that MAb 84 had higher affinity to CF
A monoclonal antibody (MAb 84) raised against the dissociated CFA/I fimbriae of enterotoxigenic Escherichia coli was characterized wi
Peptides 14VIDLL18 and 96FEAAAL101 defined as epitopes of antibodies raised against amino acid sequences of enterotoxigenic Escherichia coli colonization factor antigen I fused to Salmonella flagellin.
Luna MG, Ferreira LC, Almeida DF, Rudin A. Luna MG, et al. Microbiology. 1997 Oct;143 ( Pt 10):3201-7. doi: 10.1099/00221287-143-10-3201. Microbiology. 1997. PMID: 9353922
However, one of the hybrid flagellins (Fla II) was recognized by a previously described anti-CFA/I subunit mAb (S-CFA/I 17:8) which was able to block adhesion of CFA/I-expressing bacteria to Caco-2 cells and to bind to the amino acid sequences 15IDLLQ19 of the CFA/I fimbri …
However, one of the hybrid flagellins (Fla II) was recognized by a previously described anti-CFA/I subunit mAb (S-CFA/I 17:8) which w …
Infection with colonization factor antigen I-expressing enterotoxigenic Escherichia coli boosts antibody responses against heterologous colonization factors in primed subjects.
Rudin A, Wiklund G, Wennerås C, Qadri F. Rudin A, et al. Epidemiol Infect. 1997 Dec;119(3):391-3. doi: 10.1017/s0950268897008200. Epidemiol Infect. 1997. PMID: 9440444 Free PMC article.
Enterotoxigenic Escherichia coli (ETEC) adhere to the intestinal mucosa by a number of fimbrial colonization factors (CFs) that have been claimed to induce only type-specific immunity. ...Thus, infection with CFA/I-expressing bacteria may boost immune responses against CFs …
Enterotoxigenic Escherichia coli (ETEC) adhere to the intestinal mucosa by a number of fimbrial colonization factors (CFs) that have …
Differential kinetics and distribution of antibodies in serum and nasal and vaginal secretions after nasal and oral vaccination of humans.
Rudin A, Johansson EL, Bergquist C, Holmgren J. Rudin A, et al. Infect Immun. 1998 Jul;66(7):3390-6. doi: 10.1128/IAI.66.7.3390-3396.1998. Infect Immun. 1998. PMID: 9632610 Free PMC article.
Nasal vaccination induced 9-fold CTB-specific immunoglobulin A (IgA) and 56-fold specific IgG antibody increases in nasal secretions, whereas no significant IgA increase was seen after oral vaccination. ...A notable difference between nasal and oral vaccination was …
Nasal vaccination induced 9-fold CTB-specific immunoglobulin A (IgA) and 56-fold specific IgG antibody increases in nasal secretions, …
Identification of a cross-reactive continuous B-cell epitope in enterotoxigenic Escherichia coli colonization factor antigen I.
Rudin A, Svennerholm AM. Rudin A, et al. Infect Immun. 1996 Nov;64(11):4508-13. doi: 10.1128/IAI.64.11.4508-4513.1996. Infect Immun. 1996. PMID: 8890199 Free PMC article.
We have previously shown that a monoclonal antibody (MAb) raised against the subunits of colonization factor antigen I (CFA/I) fimbriae, which reacts with a peptide corresponding to the 25 N-terminal amino acids of such subunits, can inhibit attachment to intestinal …
We have previously shown that a monoclonal antibody (MAb) raised against the subunits of colonization factor antigen I (CFA/I) fimbri …
Monoclonal antibodies against enterotoxigenic Escherichia coli colonization factor antigen I (CFA/I) that cross-react immunologically with heterologous CFAs.
Rudin A, McConnell MM, Svennerholm AM. Rudin A, et al. Infect Immun. 1994 Oct;62(10):4339-46. doi: 10.1128/IAI.62.10.4339-4346.1994. Infect Immun. 1994. PMID: 7927693 Free PMC article.
We selected three MAbs that cross-reacted immunologically with a number of different, whole purified CFs in a dot blot test and with the corresponding subunits in sodium dodecyl sulfate-polyacrylamide gel electrophoresis. ...Moreover, it bound strongly to a p …
We selected three MAbs that cross-reacted immunologically with a number of different, whole purified CFs in a dot blot test an …
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