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Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolase enzymes.
Chem Sci. 2019 Jul 1;10(39):8995-9000. doi: 10.1039/c9sc01785b. eCollection 2019 Oct 21.
Chem Sci. 2019.
PMID: 31762980
Free PMC article.
The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism.
Rudolf AF, Kinnebrew M, Kowatsch C, Ansell TB, El Omari K, Bishop B, Pardon E, Schwab RA, Malinauskas T, Qian M, Duman R, Covey DF, Steyaert J, Wagner A, Sansom MSP, Rohatgi R, Siebold C.
Rudolf AF, et al.
Nat Chem Biol. 2019 Oct;15(10):975-982. doi: 10.1038/s41589-019-0370-y. Epub 2019 Sep 23.
Nat Chem Biol. 2019.
PMID: 31548691
Free PMC article.
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A comparison of protein kinases inhibitor screening methods using both enzymatic activity and binding affinity determination.
Rudolf AF, Skovgaard T, Knapp S, Jensen LJ, Berthelsen J.
Rudolf AF, et al.
PLoS One. 2014 Jun 10;9(6):e98800. doi: 10.1371/journal.pone.0098800. eCollection 2014.
PLoS One. 2014.
PMID: 24915177
Free PMC article.
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