Ruela-de-Sousa RR - Search Results

1

WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop.

Agajanian MJ, Walker MP, Axtman AD, Ruela-de-Sousa RR, Serafin DS, Rabinowitz AD, Graham DM, Ryan MB, Tamir T, Nakamichi Y, Gammons MV, Bennett JM, Couñago RM, Drewry DH, Elkins JM, Gileadi C, Gileadi O, Godoi PH, Kapadia N, Müller S, Santiago AS, Sorrell FJ, Wells CI, Fedorov O, Willson TM, Zuercher WJ, Major MB. Agajanian MJ, et al. Among authors: ruela de sousa rr. Cell Rep. 2019 Jan 2;26(1):79-93.e8. doi: 10.1016/j.celrep.2018.12.023. Cell Rep. 2019. PMID: 30605688 Free PMC article.

2

Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors.

Henderson SH, Sorrell F, Bennett J, Fedorov O, Hanley MT, Godoi PH, Ruela de Sousa R, Robinson S, Ashall-Kelly A, Hopkins Navratilova I, Walter DS, Elkins JM, Ward SE. Henderson SH, et al. J Med Chem. 2021 Aug 12;64(15):11709-11728. doi: 10.1021/acs.jmedchem.1c01115. Epub 2021 Aug 3. J Med Chem. 2021. PMID: 34342227 Free PMC article.

3

SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K.

Wells C, Couñago RM, Limas JC, Almeida TL, Cook JG, Drewry DH, Elkins JM, Gileadi O, Kapadia NR, Lorente-Macias A, Pickett JE, Riemen A, Ruela-de-Sousa RR, Willson TM, Zhang C, Zuercher WJ, Zutshi R, Axtman AD. Wells C, et al. Among authors: ruela de sousa rr. ACS Med Chem Lett. 2019 Oct 23;11(3):340-345. doi: 10.1021/acsmedchemlett.9b00399. eCollection 2020 Mar 12. ACS Med Chem Lett. 2019. PMID: 32184967 Free PMC article.

4

Knocking down low molecular weight protein tyrosine phosphatase (LMW-PTP) reverts chemoresistance through inactivation of Src and Bcr-Abl proteins.

Ferreira PA, Ruela-de-Sousa RR, Queiroz KC, Souza AC, Milani R, Pilli RA, Peppelenbosch MP, den Hertog J, Ferreira CV. Ferreira PA, et al. Among authors: ruela de sousa rr. PLoS One. 2012;7(9):e44312. doi: 10.1371/journal.pone.0044312. Epub 2012 Sep 5. PLoS One. 2012. PMID: 22957062 Free PMC article.

5

Calix[6]arene bypasses human pancreatic cancer aggressiveness: downregulation of receptor tyrosine kinases and induction of cell death by reticulum stress and autophagy.

Pelizzaro-Rocha KJ, de Jesus MB, Ruela-de-Sousa RR, Nakamura CV, Reis FS, de Fátima A, Ferreira-Halder CV. Pelizzaro-Rocha KJ, et al. Among authors: ruela de sousa rr. Biochim Biophys Acta. 2013 Dec;1833(12):2856-2865. doi: 10.1016/j.bbamcr.2013.07.010. Epub 2013 Jul 19. Biochim Biophys Acta. 2013. PMID: 23872419 Free article.

6

Hedgehog signaling maintains chemoresistance in myeloid leukemic cells.

Queiroz KC, Ruela-de-Sousa RR, Fuhler GM, Aberson HL, Ferreira CV, Peppelenbosch MP, Spek CA. Queiroz KC, et al. Oncogene. 2010 Dec 2;29(48):6314-22. doi: 10.1038/onc.2010.375. Epub 2010 Aug 30. Oncogene. 2010. PMID: 20802532

7

Low molecular weight protein tyrosine phosphatase (LMWPTP) upregulation mediates malignant potential in colorectal cancer.

Hoekstra E, Kodach LL, Das AM, Ruela-de-Sousa RR, Ferreira CV, Hardwick JC, van der Woude CJ, Peppelenbosch MP, Ten Hagen TL, Fuhler GM. Hoekstra E, et al. Among authors: ruela de sousa rr. Oncotarget. 2015 Apr 10;6(10):8300-12. doi: 10.18632/oncotarget.3224. Oncotarget. 2015. PMID: 25811796 Free PMC article.

8

Cytotoxicity of apigenin on leukemia cell lines: implications for prevention and therapy.

Ruela-de-Sousa RR, Fuhler GM, Blom N, Ferreira CV, Aoyama H, Peppelenbosch MP. Ruela-de-Sousa RR, et al. Cell Death Dis. 2010;1(1):e19. doi: 10.1038/cddis.2009.18. Cell Death Dis. 2010. PMID: 21364620 Free PMC article.

9

Low-Molecular-Weight Protein Tyrosine Phosphatase Predicts Prostate Cancer Outcome by Increasing the Metastatic Potential.

Ruela-de-Sousa RR, Hoekstra E, Hoogland AM, Souza Queiroz KC, Peppelenbosch MP, Stubbs AP, Pelizzaro-Rocha K, van Leenders GJLH, Jenster G, Aoyama H, Ferreira CV, Fuhler GM. Ruela-de-Sousa RR, et al. Eur Urol. 2016 Apr;69(4):710-719. doi: 10.1016/j.eururo.2015.06.040. Epub 2015 Jul 7. Eur Urol. 2016. PMID: 26159288

10

Ferruginol suppresses survival signaling pathways in androgen-independent human prostate cancer cells.

Bispo de Jesus M, Zambuzzi WF, Ruela de Sousa RR, Areche C, Santos de Souza AC, Aoyama H, Schmeda-Hirschmann G, Rodríguez JA, Monteiro de Souza Brito AR, Peppelenbosch MP, den Hertog J, de Paula E, Ferreira CV. Bispo de Jesus M, et al. Biochimie. 2008 Jun;90(6):843-54. doi: 10.1016/j.biochi.2008.01.011. Epub 2008 Feb 3. Biochimie. 2008. PMID: 18294971

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