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A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-beta activation in the kidneys of rats used as a model of diabetes.
Gong D, Lu J, Chen X, Reddy S, Crossman DJ, Glyn-Jones S, Choong YS, Kennedy J, Barry B, Zhang S, Chan YK, Ruggiero K, Phillips AR, Cooper GJ. Gong D, et al. Among authors: ruggiero k. Diabetologia. 2008 Sep;51(9):1741-51. doi: 10.1007/s00125-008-1088-7. Epub 2008 Jul 18. Diabetologia. 2008. PMID: 18636238
Copper(II)-selective chelation improves function and antioxidant defences in cardiovascular tissues of rats as a model of diabetes: comparisons between triethylenetetramine and three less copper-selective transition-metal-targeted treatments.
Lu J, Gong D, Choong SY, Xu H, Chan YK, Chen X, Fitzpatrick S, Glyn-Jones S, Zhang S, Nakamura T, Ruggiero K, Obolonkin V, Poppitt SD, Phillips AR, Cooper GJ. Lu J, et al. Among authors: ruggiero k. Diabetologia. 2010 Jun;53(6):1217-26. doi: 10.1007/s00125-010-1698-8. Epub 2010 Mar 11. Diabetologia. 2010. PMID: 20221822
Transmural differences in respiratory capacity across the rat left ventricle in health, aging, and streptozotocin-induced diabetes mellitus: evidence that mitochondrial dysfunction begins in the subepicardium.
MacDonald JR, Oellermann M, Rynbeck S, Chang G, Ruggiero K, Cooper GJ, Hickey AJ. MacDonald JR, et al. Among authors: ruggiero k. Am J Physiol Cell Physiol. 2011 Feb;300(2):C246-55. doi: 10.1152/ajpcell.00294.2010. Epub 2010 Nov 17. Am J Physiol Cell Physiol. 2011. PMID: 21084644
Psychological trauma and the genetic overlap between posttraumatic stress disorder and major depressive disorder.
Mundy J, Hübel C, Gelernter J, Levey D, Murray RM, Skelton M, Stein MB; Million Veteran Program, Post Traumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium, Vassos E, Breen G, Coleman JRI. Mundy J, et al. Psychol Med. 2021 Jun 4:1-10. doi: 10.1017/S0033291721000830. Online ahead of print. Psychol Med. 2021. PMID: 34085609
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