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The epidermal growth factor receptor and its ligands as therapeutic targets in human tumors.
Rusch V, Mendelsohn J, Dmitrovsky E. Rusch V, et al. Cytokine Growth Factor Rev. 1996 Aug;7(2):133-41. doi: 10.1016/1359-6101(96)00016-0. Cytokine Growth Factor Rev. 1996. PMID: 8899291 Review.
Inhibited transformation of immortalized human bronchial epithelial cells by retinoic acid is linked to cyclin E down-regulation.
Langenfeld J, Lonardo F, Kiyokawa H, Passalaris T, Ahn MJ, Rusch V, Dmitrovsky E. Langenfeld J, et al. Among authors: rusch v. Oncogene. 1996 Nov 7;13(9):1983-90. Oncogene. 1996. PMID: 8934545
Growth suppression of transformed human bronchial epithelial cells by all-trans-retinoic acid occurs through specific retinoid receptors.
Ahn MJ, Langenfeld J, Moasser MM, Rusch V, Dmitrovsky E. Ahn MJ, et al. Among authors: rusch v. Oncogene. 1995 Dec 7;11(11):2357-64. Oncogene. 1995. PMID: 8570187
Cyclin D1 proteolysis: a retinoid chemoprevention signal in normal, immortalized, and transformed human bronchial epithelial cells.
Boyle JO, Langenfeld J, Lonardo F, Sekula D, Reczek P, Rusch V, Dawson MI, Dmitrovsky E. Boyle JO, et al. Among authors: rusch v. J Natl Cancer Inst. 1999 Feb 17;91(4):373-9. doi: 10.1093/jnci/91.4.373. J Natl Cancer Inst. 1999. PMID: 10050872
Overexpression of cyclins D1 and E is frequent in bronchial preneoplasia and precedes squamous cell carcinoma development.
Lonardo F, Rusch V, Langenfeld J, Dmitrovsky E, Klimstra DS. Lonardo F, et al. Among authors: rusch v. Cancer Res. 1999 May 15;59(10):2470-6. Cancer Res. 1999. PMID: 10344760
An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors.
Chitale D, Gong Y, Taylor BS, Broderick S, Brennan C, Somwar R, Golas B, Wang L, Motoi N, Szoke J, Reinersman JM, Major J, Sander C, Seshan VE, Zakowski MF, Rusch V, Pao W, Gerald W, Ladanyi M. Chitale D, et al. Among authors: rusch v. Oncogene. 2009 Aug 6;28(31):2773-83. doi: 10.1038/onc.2009.135. Epub 2009 Jun 15. Oncogene. 2009. PMID: 19525976 Free PMC article.
Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does not predict tumor progression.
Rusch V, Klimstra D, Venkatraman E, Pisters PW, Langenfeld J, Dmitrovsky E. Rusch V, et al. Clin Cancer Res. 1997 Apr;3(4):515-22. Clin Cancer Res. 1997. PMID: 9815714
A phase II trial of pleurectomy/decortication followed by intrapleural and systemic chemotherapy for malignant pleural mesothelioma.
Rusch V, Saltz L, Venkatraman E, Ginsberg R, McCormack P, Burt M, Markman M, Kelsen D. Rusch V, et al. J Clin Oncol. 1994 Jun;12(6):1156-63. doi: 10.1200/JCO.1994.12.6.1156. J Clin Oncol. 1994. PMID: 8201377 Clinical Trial.
High telomerase activity in primary lung cancers: association with increased cell proliferation rates and advanced pathologic stage.
Albanell J, Lonardo F, Rusch V, Engelhardt M, Langenfeld J, Han W, Klimstra D, Venkatraman E, Moore MA, Dmitrovsky E. Albanell J, et al. Among authors: rusch v. J Natl Cancer Inst. 1997 Nov 5;89(21):1609-15. doi: 10.1093/jnci/89.21.1609. J Natl Cancer Inst. 1997. PMID: 9362159
Aberrant expression of p53 or the epidermal growth factor receptor is frequent in early bronchial neoplasia and coexpression precedes squamous cell carcinoma development.
Rusch V, Klimstra D, Linkov I, Dmitrovsky E. Rusch V, et al. Cancer Res. 1995 Mar 15;55(6):1365-72. Cancer Res. 1995. PMID: 7882337
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